Department of Gastroenterology, Huaibei People's Hospital, Huaibei People's Hospital affiliated to Bengbu Medical College, Huaibei, Anhui Province, China.
Scand J Gastroenterol. 2024 Aug;59(8):900-905. doi: 10.1080/00365521.2024.2368250. Epub 2024 Jun 18.
To observe the clinical therapeutic effect and mental state of mindfulness-based cognitive therapy (MBCT) in patients with functional dyspepsia (FD).
In this study, 80 patients suffering from FD in an outpatient clinic were enrolled from January to December 2020. Patients were randomly allocated into the control group (conventional treatment) and observation group (MBCT treatment). Patients in the control group were prescribed rabeprazole and mosapiride, and patients in the observation group were given MBCT therapy in addition to the above drugs. After treatment for 8 weeks, the changes in gastrointestinal symptom scores, anxiety, depression, mindfulness and sleep quality and gastric emptying testing were compared between these two groups.
The observation group showed strikingly lower gastrointestinal symptom scores, SAS, SDS, PSQI, and SCL-90 scale scores, and higher FFMQ scale scores than the control group ( < 0.05). There was no conspicuous change in gastric emptying monitoring ( > 0.05).
MBCT therapy can improve patients' gastrointestinal symptoms, attenuate their anxiety and depression levels, and ameliorate their sleep quality.
观察正念认知疗法（MBCT）对功能性消化不良（FD）患者的临床疗效及心理状态的影响。
选取 2020 年 1 月至 12 月我院门诊收治的 80 例 FD 患者，采用随机数字表法将患者分为对照组（常规治疗）和观察组（MBCT 治疗），每组 40 例。对照组患者给予雷贝拉唑、枸橼酸莫沙必利治疗，观察组患者在对照组治疗的基础上给予 MBCT 治疗，疗程均为 8 周。比较两组患者治疗前后的胃肠道症状评分、焦虑、抑郁、正念和睡眠质量以及胃排空检测的变化。
观察组患者的胃肠道症状评分、SAS、SDS、PSQI、SCL-90 量表评分显著低于对照组（均<0.05），FFMQ 量表评分显著高于对照组（均<0.05）；两组患者胃排空监测结果比较差异无统计学意义（均>0.05）。
MBCT 治疗可改善患者的胃肠道症状，减轻焦虑、抑郁程度，提高睡眠质量。
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