体外绘制小鼠轴向祖细胞动力学图谱。

Mapping mouse axial progenitor dynamics in vitro.

机构信息

Department of Genetics, Harvard Medical School, Boston, MA, USA; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

Department of Genetics, Harvard Medical School, Boston, MA, USA; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA.

出版信息

Dev Cell. 2024 Jun 17;59(12):1487-1488. doi: 10.1016/j.devcel.2024.05.026.

DOI:10.1016/j.devcel.2024.05.026

PMID:38889690

Abstract

In this issue of Developmental Cell, Bolondi et al. systematically assesses neuro-mesodermal progenitor (NMP) dynamics by combining a mouse stem-cell-based embryo model with molecular recording of single cells, shedding light on the dynamics of neural tube and paraxial mesoderm formation during mammalian development.

摘要

在本期《发育细胞》中，Bolondi 等人通过结合基于小鼠干细胞的胚胎模型和单细胞的分子记录，系统地评估了神经中胚层祖细胞（NMP）的动力学，揭示了哺乳动物发育过程中神经管和轴旁中胚层形成的动力学。