Rosen S, Beck F M, Beck E X
J Dent Res. 1985 Jun;64(6):904-5. doi: 10.1177/00220345850640060901.
A sodium fluoride-containing dentifrice (Gleem) was evaluated for its efficacy to inhibit root surface caries in the rice rat. The dentifrice was diluted 50/50 with water so that the slurry contained 500 ppm fluoride. This slurry, a solution of 5000 ppm fluoride, and demineralized water were applied to the molar teeth twice daily for 10 weeks. Another group of rats was given 50 ppm fluoride in the drinking water. There was significantly less root surface caries in all groups of rats which received fluoride than in the demineralized water control animals. However, none of the fluoride preparations inhibited the loss of alveolar bone.
对一种含氟化钠的牙膏（佳洁士）进行了评估，以确定其抑制稻鼠根面龋的功效。将牙膏与水按1:1稀释，使牙膏糊含氟量为500 ppm。将该牙膏糊、5000 ppm的氟溶液和去离子水每天两次涂抹于磨牙，持续10周。另一组大鼠饮用含50 ppm氟的水。所有接受氟处理的大鼠组的根面龋明显少于去离子水对照动物组。然而，没有一种氟制剂能抑制牙槽骨的流失。
