Amato Annalisa, Cavallo Carmelo, Marín-García Pablo Jesús, Emmanuele Giovanni, Tomasello Mario, Tomasella Cristina, Floridia Viviana, Liotta Luigi, Llobat Lola
Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Departamento Producción y Sanidad Animal, Salud Pública y Ciencia y Tecnología de los Alimentos (PASAPTA), Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46113 Valencia, Spain.
Animals (Basel). 2024 May 21;14(11):1516. doi: 10.3390/ani14111516.
Dogs are considered the main reservoir of several zoonoses endemic to the Mediterranean Basin. In this study, a prevalence of infections and coinfections of canine vector-borne diseases was analyzed in apparently healthy dogs of different canine pure breeds in Sicily (Italy), where these diseases are endemic. The seroprevalence of , , , and was assessed, as single and coinfections. Biochemical and hematological parameters were evaluated, and epidemiological factors, including sex, age, and canine breed, were recovered. The most frequent infection was (45.61%), following (36.84%), both as single, double, or triple coinfections. Coinfections change the biochemical and hematological parameters of the host, and canine breeds are related to the infection frequency and the parameters observed during infections. Changes in the complete blood count (CBC) and biochemical values also differ between canine breeds, with the Cirneco dell'Etna dogs infected with being the animals presenting the most interesting results in our study. High values of RBC, hemoglobin, hematocrit, mean corpuscular hemoglobin (MCH), the albumin/globulin (A/G) ratio, and albumin and low levels of β-2 globulin and γ-globulin were found only in this canine breed, suggesting some resistance to infection in these dogs. Future studies about the immune response of this canine breed could be interesting to determine their possible resistance to zoonotic pathogens, such as .
狗被认为是地中海盆地几种地方性人畜共患病的主要宿主。在本研究中，对意大利西西里岛不同犬种的看似健康的狗进行了犬媒传播疾病感染和混合感染的患病率分析，这些疾病在该地区呈地方性流行。评估了无形体病、巴贝斯虫病、埃立克体病和莱姆病的血清阳性率，包括单一感染和混合感染情况。评估了生化和血液学参数，并收集了包括性别、年龄和犬种在内的流行病学因素。最常见的感染是无形体病（45.61%），其次是巴贝斯虫病（36.84%），二者均可为单一感染、双重感染或三重感染。混合感染会改变宿主的生化和血液学参数，犬种与感染频率以及感染期间观察到的参数有关。不同犬种的全血细胞计数（CBC）和生化值变化也有所不同，在我们的研究中，感染无形体病的埃特纳火山犬呈现出最有趣的结果。仅在这个犬种中发现红细胞、血红蛋白、血细胞比容、平均红细胞血红蛋白（MCH）、白蛋白/球蛋白（A/G）比值和白蛋白值较高，而β-2球蛋白和γ-球蛋白水平较低，这表明这些狗对感染具有一定的抵抗力。关于这个犬种免疫反应的未来研究可能有助于确定它们对人畜共患病原体（如无形体）的潜在抵抗力。
