Eating Disorders Center, Department of Neuroscience "Rita Levi Montalcini", University of Turin, Via Cherasco 11, 10126 Turin, Italy.
Nutrients. 2024 May 29;16(11):1664. doi: 10.3390/nu16111664.
The choice of a refeeding strategy is essential in the inpatient treatment of Anorexia Nervosa (AN). Oral nutrition is usually the first choice, but enteral nutrition through the use of a Nasogastric Tube (NGT) often becomes necessary in hospitalized patients. The literature provides mixed results on the efficacy of this method in weight gain, and there is a scarcity of studies researching its psychological correlates. This study aims to analyze the effectiveness of oral versus enteral refeeding strategies in inpatients with AN, focusing on Body Mass Index (BMI) increase and treatment satisfaction, alongside assessing personality traits. We analyzed data from 241 inpatients, comparing a group of treated vs. non-treated individuals, balancing confounding factors using propensity score matching, and applied regression analysis to matched groups. The findings indicate that enteral therapy significantly enhances BMI without impacting treatment satisfaction, accounting for the therapeutic alliance. Personality traits showed no significant differences between patients undergoing oral or enteral refeeding. The study highlights the clinical efficacy of enteral feeding in weight gain, supporting its use in severe AN cases when oral refeeding is inadequate without adversely affecting patient satisfaction or being influenced by personality traits.
在神经性厌食症（AN）的住院治疗中，选择喂养策略至关重要。口服营养通常是首选，但住院患者通常需要通过使用鼻胃管（NGT）进行肠内营养。文献对这种方法在体重增加方面的疗效提供了混合的结果，并且研究其心理相关性的研究很少。本研究旨在分析口服与肠内喂养策略在 AN 住院患者中的有效性，重点关注体重指数（BMI）的增加和治疗满意度，并评估人格特质。我们分析了 241 名住院患者的数据，比较了治疗组和非治疗组，使用倾向评分匹配平衡混杂因素，并对匹配组应用回归分析。研究结果表明，肠内治疗显著增加 BMI，而不影响治疗满意度，这与治疗联盟有关。人格特质在接受口服或肠内喂养的患者之间没有显著差异。该研究强调了肠内喂养在体重增加方面的临床疗效，支持在口服喂养不足的严重 AN 病例中使用肠内喂养，而不会对患者满意度产生不利影响，也不会受人格特质的影响。
