Dhopatkar Namrata, Keeler Johanna L, Gravina Davide, Gower Jacinda, Mutwalli Hiba, Bektas Sevgi, Fuller Sarah J, Himmerich Hubertus, Treasure Janet
South London and Maudsley NHS Foundation Trust, London SE5 8AZ, UK.
Centre for Research in Eating and Weight Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College, London SE5 8AF, UK.
Nutrients. 2025 Jan 24;17(3):425. doi: 10.3390/nu17030425.
: Anorexia nervosa and atypical anorexia nervosa require refeeding as a core part of their treatment, and enteral tube nutrition (ETN) may be needed in some individuals either to supplement or replace oral nutrition. This scoping review aimed to explore outcomes associated with phases of ETN, including initial nutrition, transition from enteral nutrition to oral intake, and to overall nutrition; : The Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews checklist was used. A systematic search was performed using the Ovid and the Web of Science databases, using relevant search terms identifying 37 studies to be included in the review. Quantitative and qualitative data were synthesised and presented; : ETN resulted in similar or higher weight gain than oral nutrition. Refeeding syndrome parameters were comparable between ETN and oral nutrition with some indication that prophylactic phosphate supported mitigation of hypophosphataemia. Global psychological parameters related to the eating disorder improved with nutrition; however, there was an indication that weight and shape concerns did not improve during this period. There was a lack of evidence related to transition from ETN to oral intake. Qualitative data indicated meanings attached to the tube, suggesting that additional support may be needed for the transition away from the tube. Furthermore, consideration may be required to support individuals in mitigating trauma related to ETN under restraint; : ETN, when required, is a viable alternative to oral intake. Results indicated the need for further research, especially in the transition from ETN to oral intake with regard to strategies of transition and support, and outcomes related to these strategies.
神经性厌食症和非典型神经性厌食症的治疗核心部分是重新喂养，一些患者可能需要肠内管饲营养（ETN）来补充或替代口服营养。本范围综述旨在探讨与ETN各阶段相关的结果，包括初始营养、从肠内营养过渡到口服摄入以及总体营养情况。使用了系统评价和Meta分析扩展版的范围综述清单。通过Ovid和Web of Science数据库进行系统检索，使用相关检索词确定了37项研究纳入综述。对定量和定性数据进行了综合和呈现。ETN导致的体重增加与口服营养相似或更高。ETN和口服营养之间的再喂养综合征参数相当，有迹象表明预防性补充磷酸盐有助于减轻低磷血症。与饮食失调相关的整体心理参数随着营养状况的改善而改善；然而，有迹象表明在此期间对体重和体型的关注并未改善。缺乏与从ETN过渡到口服摄入相关的证据。定性数据表明了管子所具有的意义，这表明在脱离管子的过渡过程中可能需要额外的支持。此外，可能需要考虑为个体提供支持，以减轻与约束下的ETN相关的创伤。当需要时，ETN是口服摄入的可行替代方案。结果表明需要进一步研究，特别是在从ETN过渡到口服摄入方面，涉及过渡策略和支持以及与这些策略相关的结果。
