Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Wickenburg Str. 21, 45147 Essen, Germany.
Center for Translational Neuro and Behavioral Sciences, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Nutrients. 2024 May 31;16(11):1732. doi: 10.3390/nu16111732.
The variation in body mass index (BMI) of inpatients with anorexia nervosa has not been analyzed across the age span. A positive correlation between BMI and age has been reported in adolescent inpatients aged 15 years and younger that levels off at 15 to 18 years. BMIs standardized for age and sex (standard deviation scores, SDSs) were negatively correlated with age in these inpatients aged 8 to 18 years.
The aims of the current retrospective study were threefold: first, to confirm the relationships of BMI, BMI-SDS and age in adolescent inpatients in a larger sample; second, to systematically assess the relationship of BMI, BMI-SDS, body height-SDS and age in adult inpatients at the time of referral; and third, to assess body height-SDSs and age to evaluate stunting.
We included 1001 girls (aged 12-17.9 years) and 1371 women (aged 18-73 years) admitted to inpatient treatment between 2014 and 2021. Mean BMI at admission was 14.95 kg/m (SD = 1.43; range 10.67-18.47) in adolescents and 14.63 kg/m (SD = 2.02; range 8.28-18.47) in adults. None of the adolescent patients but 20 adults had very low BMI values below 10 kg/m. Adolescents showed a small but significant positive correlation between age and BMI (r = 0.12; = 2.4 × 10). In adults, BMI was not correlated with age (r = -0.03; = 0.3). BMI-SDSs was negatively correlated with age in adolescents and less so in adults (r = -0.35; < 0.001 and r = -0.09; = 0.001). Curve fit analyses for all patients indicated that there was a quadratic (age × age) relationship between age and BMI-SDS. Height correlated positively with BMI in adult (r = 0.1; < 0.001) and adolescent (r = 0.09 = 0.005) patients and we detected no evidence for stunting.
In conclusion, the BMI of inpatients seems to be relatively stable across the age span with mean values between 14 and 15 kg/m. BMI values initially increase with age in younger patients, drop between ages 18 and 23 and then slowly decline with age.
神经性厌食症住院患者的体重指数 (BMI) 随年龄的变化尚未在整个年龄范围内进行分析。在年龄在 15 岁及以下的青少年住院患者中，BMI 与年龄呈正相关，在 15 至 18 岁时趋于平稳。在年龄在 8 至 18 岁的这些住院患者中，BMI 标准化为年龄和性别（标准偏差分数，SDS）与年龄呈负相关。
本回顾性研究的目的有三：首先，在更大的样本中确认青少年住院患者 BMI、BMI-SDS 和年龄之间的关系；其次，系统评估成年住院患者就诊时 BMI、BMI-SDS、身高-SDS 和年龄之间的关系；并评估身高-SDS 和年龄以评估生长迟缓。
我们纳入了 2014 年至 2021 年间住院治疗的 1001 名女孩（年龄 12-17.9 岁）和 1371 名女性（年龄 18-73 岁）。入院时青少年的平均 BMI 为 14.95kg/m（SD=1.43；范围 10.67-18.47），成年女性为 14.63kg/m（SD=2.02；范围 8.28-18.47）。没有青少年患者，但有 20 名成年患者的 BMI 值非常低，低于 10kg/m。青少年的 BMI 与年龄呈小但显著的正相关（r=0.12；p=2.4×10）。在成年人中，BMI 与年龄不相关（r=-0.03；p=0.3）。青少年 BMI-SDS 与年龄呈负相关，而成人则呈较弱的负相关（r=-0.35；p<0.001 和 r=-0.09；p=0.001）。所有患者的曲线拟合分析表明，BMI-SDS 与年龄之间存在二次（年龄×年龄）关系。身高与成年（r=0.1；p<0.001）和青少年（r=0.09；p=0.005）患者的 BMI 呈正相关，我们未发现发育迟缓的证据。
总之，住院患者的 BMI 似乎在整个年龄范围内相对稳定，平均值在 14 至 15kg/m 之间。在年轻患者中，BMI 值最初随年龄增长而增加，在 18 至 23 岁之间下降，然后随年龄缓慢下降。
