Students Scientific Club of Dietetics, Institute of Health Sciences, Medical College of Rzeszow University, 35-959 Rzeszow, Poland.
Department of Physiotherapy, Faculty of Health Sciences, Jagiellonian University Medical College, 31-008 Kraków, Poland.
Nutrients. 2024 Jun 5;16(11):1767. doi: 10.3390/nu16111767.
The nutritional status of the mother-to-be has a key impact on the proper development of the fetus. Although all nutrients are important for the developing baby, recent research indicates the importance of adequate choline intake during the periconceptional period, pregnancy, and lactation. Choline plays a key role in the biosynthesis of cell membranes, supporting liver function, neurotransmission, brain development, and DNA and histone methylation. Choline participates in the formation of a child's nervous system, supports its cognitive development, and reduces the risk of neural tube defects. The human body is incapable of producing sufficient choline to meet its needs; therefore, it must be obtained from the diet. Current data indicate that most women in their reproductive years do not achieve the recommended daily intake of choline. The presented narrative review indicates the importance of educating mothers-to-be and thereby increasing their awareness of the effects of choline on maternal and child health, which can lead to a more aware and healthy pregnancy and proper child development.
孕妇的营养状况对胎儿的正常发育有重要影响。虽然所有的营养物质对发育中的婴儿都很重要,但最近的研究表明,在受孕前、怀孕期和哺乳期摄入足够的胆碱非常重要。胆碱在细胞膜的生物合成中起着关键作用,支持肝功能、神经递质传递、大脑发育以及 DNA 和组蛋白甲基化。胆碱参与儿童神经系统的形成,支持其认知发展,并降低神经管缺陷的风险。人体自身无法产生足够的胆碱来满足需求,因此必须从饮食中获取。目前的数据表明,大多数育龄妇女没有达到推荐的胆碱日摄入量。本综述指出,对孕妇进行教育从而提高她们对胆碱对母婴健康影响的认识非常重要,这可以导致更有意识和健康的怀孕以及适当的儿童发育。