Department of Medicine, Division of Cardiology, Einstein Institute for Aging Research, Montefiore Health System, New York, NY, United States.
University of Naples "Federico II", Naples, Italy.
Front Endocrinol (Lausanne). 2023 Mar 7;14:1148166. doi: 10.3389/fendo.2023.1148166. eCollection 2023.
In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (CHNOP), also known as alpha-glycerophosphocholine (α-GPC, or GPC), choline bitartrate, lecithin, and citicoline, which are cholinergic compounds and precursors of acetylcholine. Extensively used as food supplements, they have been shown to represent an effective strategy for boosting memory and enhancing cognitive function.
在这篇全面的综述中,我们研究了评估目前可用的不同形式胆碱补充剂效果的主要临床前和临床研究,包括胆碱酒石酸氢盐(CHNOP),也称为α-甘油磷酸胆碱(α-GPC,或 GPC)、胆碱酒石酸盐、卵磷脂和胞磷胆碱,它们都是胆碱能化合物和乙酰胆碱的前体。作为食品补充剂广泛使用,已证明它们是提高记忆力和增强认知功能的有效策略。