Abousifein Marfy, Shishkina Anna, Leyland Nicholas
Health Sciences Department, McMaster University, Hamilton, ON L8S 4L8, Canada.
McMaster University Medical Center, Hamilton, ON L8N 3Z5, Canada.
J Clin Med. 2024 May 28;13(11):3155. doi: 10.3390/jcm13113155.
In light of increased cesarean section rates, the incidence of placenta accreta spectrum (PAS) disorder is increasing. Despite the establishment of clinical practice guidelines offering recommendations for early and effective PAS diagnosis and treatment, antepartum diagnosis of PAS remains a challenge. This ultimately risks poor mental health and poor physical maternal and neonatal health outcomes.
This case series details the experience of two high-risk patients who remained undiagnosed for PAS until they presented with antenatal hemorrhage, leading ultimately to necessary, complex surgical interventions, which can only be optimally provide in a tertiary care center. Patient 1 is a 37-year-old woman with a history of three cesarean sections, which elevates her risk for PAS. She had placenta previa detected at 19 weeks, and placenta percreta diagnosed upon hemorrhage. During a hysterectomy, invasive placenta was found in the patient's bladder, leading to a cystotomy and right ureteric reimplantation. After discharge, she was diagnosed with a vesicovaginal fistula, and is currently awaiting surgical repair. Patient 2 is a 34-year-old woman with two previous cesarean sections. The patient had complete placenta previa detected at 19- and 32-week gestation scans. She presented with antepartum hemorrhage at 35 weeks and 2 days. An ultrasound showed thin myometrium at the scar site with significant vascularity. A hysterectomy was performed due to placental attachment issues, with significant blood loss. Both patients were at high risk for PAS based on past medical history, risk factors, and pathognomonic imaging findings.
We highlight the importance of the implementation of clinical guidelines at non-tertiary healthcare centers. We offer clinical-guideline-informed recommendations for radiologists and antenatal care providers to promote early PAS diagnosis and, ultimately, better patient and neonatal outcomes through increased access to adequate care.
鉴于剖宫产率上升,胎盘植入谱系障碍(PAS)的发病率也在增加。尽管已经制定了临床实践指南,为PAS的早期有效诊断和治疗提供了建议,但产前诊断PAS仍然是一项挑战。这最终会导致产妇心理健康不佳,以及产妇和新生儿的身体状况不佳。
本病例系列详细介绍了两名高危患者的经历,她们在产前出血之前一直未被诊断出患有PAS,最终导致了必要的复杂手术干预,而这些干预只有在三级医疗中心才能得到最佳实施。患者1是一名37岁的女性,有三次剖宫产史,这增加了她患PAS的风险。她在孕19周时被诊断为前置胎盘,出血时被诊断为穿透性胎盘植入。在子宫切除术中,发现患者膀胱中有侵袭性胎盘,导致膀胱切开术和右侧输尿管再植术。出院后,她被诊断出患有膀胱阴道瘘,目前正在等待手术修复。患者2是一名34岁的女性,有两次剖宫产史。该患者在孕19周和32周的超声检查中均被诊断为完全性前置胎盘。她在孕35周零2天时出现产前出血。超声显示瘢痕部位子宫肌层变薄,血管丰富。由于胎盘附着问题,患者进行了子宫切除术,术中出血量大。根据既往病史、危险因素和特征性影像学表现,两名患者均为PAS高危人群。
我们强调在非三级医疗中心实施临床指南的重要性。我们为放射科医生和产前护理人员提供基于临床指南的建议,以促进PAS的早期诊断,并最终通过增加获得适当护理的机会,改善患者和新生儿的结局。