Zimmermann W
Zentralbl Bakteriol Orig A. 1979 Jun;244(1):58-72.
It is demonstrated that it is possible to change the stereotyped reaction of the steroid metabolism to infection by means of external influences. The progress of infectious diseases can be detoriated and the average duration of life can be shortened by rearing a special strain of test rabbits or by lack of protein in the diet, by blocking the RES, by cortisol, estradiol and thyroxin, by glucose and by polyvinylpyridin-N-oxid. - The time of survival is prolonged by testosterone, dehydroepiandrosterone and cyproterone, also by cystein, aristolochia acid and treatment with pyrifer. - No effect whatever on the progress of an infectious disease is produced by the vitamines A, B1, B6, D, E and especially ascorbinic acid, also an extract of thymus gland, spleen, insulin, a preparation with STH, and Norgestrel, DMSO and treatment with B, bifidum and with omnadin.
已证明,通过外部影响改变类固醇代谢对感染的刻板反应是可能的。饲养特殊品系的实验兔、饮食中缺乏蛋白质、阻断网状内皮系统、使用皮质醇、雌二醇和甲状腺素、葡萄糖以及聚乙烯吡啶-N-氧化物,会使传染病病情恶化,缩短平均寿命。睾酮、脱氢表雄酮和环丙孕酮,还有半胱氨酸、马兜铃酸以及用梨形虫处理,可延长存活时间。维生素A、B1、B6、D、E,尤其是抗坏血酸,还有胸腺、脾脏提取物、胰岛素、生长激素制剂、炔诺孕酮、二甲基亚砜以及用双歧杆菌和奥姆那丁处理,对传染病的进程均无任何影响。