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酷似支气管哮喘的声门下腺样囊性癌:一例报告

Subglottic Adenoid Cystic Carcinoma Mimicking Bronchial Asthma: A Case Report.

作者信息

Athish K K, T J Guruprasad, Padmanabha Spurthy, K R Harshitha

机构信息

Internal Medicine, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, IND.

Respiratory Medicine, Sri Devaraj Urs Medical College, Kolar, IND.

出版信息

Cureus. 2024 May 18;16(5):e60571. doi: 10.7759/cureus.60571. eCollection 2024 May.

Abstract

Adenoid cystic carcinoma (ACC) is a rare type of tumor that usually originates from minor salivary glands in the oral cavity. ACC of the larynx is even rare. This case study describes a 36-year-old non-smoking male farmer who initially presented with dyspnea and was misdiagnosed with bronchial asthma. Spirometry revealed fixed airway obstruction. Further evaluation revealed a pedunculated mass obstructing the airway, which was diagnosed as ACC by histopathological examination of the biopsy specimen. The patient was treated with radiation therapy, resulting in clinical improvement after six weeks. ACC is highly invasive and slow-growing, with perineural extension and a higher risk of recurrence. Metastasis in the lungs is common. Adequate preoperative staging, including imaging with computed tomography (CT) and magnetic resonance imaging, is important for planning treatment. The role of radiation therapy with concurrent chemotherapy is still under trial.

摘要

腺样囊性癌(ACC)是一种罕见的肿瘤类型,通常起源于口腔中的小唾液腺。喉腺样囊性癌更为罕见。本病例研究描述了一名36岁不吸烟的男性农民,最初表现为呼吸困难,被误诊为支气管哮喘。肺功能测定显示存在固定性气道阻塞。进一步评估发现一个带蒂肿物阻塞气道,经活检标本的组织病理学检查诊断为腺样囊性癌。该患者接受了放射治疗,六周后临床症状有所改善。腺样囊性癌具有高度侵袭性且生长缓慢,易沿神经蔓延,复发风险较高。肺转移很常见。充分的术前分期,包括计算机断层扫描(CT)和磁共振成像等影像学检查,对于制定治疗方案很重要。同步放化疗的作用仍在试验中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd2b/11183517/b87c10a0bc25/cureus-0016-00000060571-i01.jpg

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