Wali Junaid A, Robinson Shannon, Green Steven
Department of Internal Medicine Jacobs School of Medicine and Biomedical Sciences, University at Buffalo Buffalo New York USA.
Department of Hematology Roswell Park Comprehensive Cancer Center Buffalo New York USA.
EJHaem. 2024 May 16;5(3):589-592. doi: 10.1002/jha2.900. eCollection 2024 Jun.
Platelet satellitism refers to the rosetting of the platelets around white blood cells, mostly neutrophils that could lead to spuriously low platelet counts on automated analyzers. The phenomenon has usually been described in EDTA processed blood samples. We describe the clinical course of a patient with immune thrombocytopenia with platelet satellitism in both EDTA as well as non EDTA processed blood samples. We also review the literature describing two other reports of the platelet satellitism in patients with immune thrombocytopenia. We also reference the literature describing the heterogeneity of the presence of platelet satellitism in different clinical and laboratory settings.
血小板卫星现象是指血小板围绕白细胞形成玫瑰花环,主要是围绕中性粒细胞,这可能导致自动分析仪上血小板计数假性降低。这种现象通常在乙二胺四乙酸(EDTA)处理的血液样本中被描述。我们描述了一名免疫性血小板减少症患者在EDTA处理和非EDTA处理的血液样本中均出现血小板卫星现象的临床过程。我们还回顾了文献中描述的另外两例免疫性血小板减少症患者出现血小板卫星现象的报告。我们也参考了描述血小板卫星现象在不同临床和实验室环境中存在异质性的文献。