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铝厂诱变剂检测。对暴露工人痰液进行鼠伤寒沙门氏菌试验的结果。

Testing for mutagens in an aluminium plant. The results of Salmonella typhimurium tests on expectorates from exposed workers.

作者信息

Krøkje A, Tiltnes A, Mylius E, Gullvåg B

出版信息

Mutat Res. 1985 Jun;156(3):147-52. doi: 10.1016/0165-1218(85)90057-6.

DOI:10.1016/0165-1218(85)90057-6
PMID:3889632
Abstract

Methanol extracts of hydrolyzed expectorate samples from workers in a Söderberg potroom were evaluated by the Salmonella reversion assay. The expectorates from exposed workers--mostly from smokers, but also to a certain extent from nonsmokers--were mutagenic; however, the control samples from both smokers and nonsmokers were not. The positive results produced by the expectorate samples from the exposed smokers suggest a synergistic relationship between exposure to air pollution of the working atmosphere and smoking.

摘要

采用沙门氏菌回复突变试验对来自一个索德伯格电极焙烧车间工人的水解咳出物样品的甲醇提取物进行了评估。暴露工人的咳出物——大多来自吸烟者,但在一定程度上也来自不吸烟者——具有致突变性;然而,吸烟者和不吸烟者的对照样品均无致突变性。暴露吸烟者咳出物样品产生的阳性结果表明,工作环境空气污染暴露与吸烟之间存在协同关系。

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