Hand Surgeon, Department of Orthopedics and Traumatology, Escola Paulista de Medicina - Universidade Federal de São Paulo (EPM-UNIFESP), São Paulo (SP), Brazil.
Adjunct Professor, Department of Orthopedics and Traumatology. Discipline of Hand and Upper Limb Surgery, Escola Paulista de Medicina - Universidade Federal de São Paulo (EPMUNIFESP), São Paulo (SP), Brazil.
Sao Paulo Med J. 2024 Jun 17;142(6):e2023349. doi: 10.1590/1516-3180.2023.0349.R1.08042024. eCollection 2024.
Congenital Anomalies of the Upper Limb (CAUL) are a group of structural or functional abnormalities that develop during intrauterine life and can lead to limb dysfunction.
To analyze the prevalence of congenital anomalies of the upper limbs in Brazil and assess maternal and neonatal variables.
A cross-sectional, descriptive study was conducted on congenital upper limb malformations among live births across Brazil.
The study spanned from 2010 to 2019. Data were sourced from the Department of Informatics of the Unified Health System (DATASUS) and the Live Birth Information System (SINASC) portal. Analyses focused on the information reported in field 41 of the Live Birth Declaration Form entered into the computerized system.
The most common anomaly in Brazil was supernumerary fingers, classified as ICD-Q69.0, affecting 11,708 children, with a prevalence of 4.02 per 10,000 live births. Mothers aged over 40 years had a 36% higher prevalence of having children with CAUL than mothers under 40 years old (OR = 1.36; 95% CI 1.19-1.56). Newborns weighing ≥ 2,499 g were 2.64 times more likely to have CAUL compared to those weighing ≥ 2,500 g (OR = 2.64; 95% CI 2.55-2.73).
There was an observed increase in the reporting of CAUL cases over the decade studied. This trend serves as an alert for health agencies, as understanding the prevalence of CAUL and its associated factors is crucial for preventive medicine.
上肢先天畸形（CAUL）是一组在宫内发育过程中发生的结构或功能异常，可导致肢体功能障碍。
分析巴西上肢先天畸形的流行情况，并评估母婴和新生儿变量。
这是一项在巴西进行的涉及活产儿上肢先天畸形的横断面描述性研究。
研究时间跨度为 2010 年至 2019 年。数据来源于统一卫生系统（DATASUS）和活产信息系统（SINASC）门户的信息。分析重点是在计算机系统中输入的活产声明表第 41 字段中报告的信息。
巴西最常见的上肢先天畸形是多指畸形，分类为 ICD-Q69.0，影响了 11708 名儿童，每 10000 例活产儿中有 4.02 例。年龄超过 40 岁的母亲所生孩子患有 CAUL 的患病率比年龄在 40 岁以下的母亲高 36%（OR=1.36；95%CI 1.19-1.56）。体重≥2499g 的新生儿发生 CAUL 的可能性是体重≥2500g 新生儿的 2.64 倍（OR=2.64；95%CI 2.55-2.73）。
在所研究的十年中，CAUL 病例的报告呈上升趋势。这一趋势提醒了卫生机构，因为了解 CAUL 的流行情况及其相关因素对于预防医学至关重要。
