巴西的小头畸形：2000 - 2015年活产信息系统（Sinasc）中病例的患病率及特征
Microcephaly in Brazil: prevalence and characterization of cases from the Information System on Live Births (Sinasc), 2000-2015.
作者信息
Marinho Fatima, Araújo Valdelaine Etelvina Miranda de, Porto Denise Lopes, Ferreira Helena Luna, Coelho Marta Roberta Santana, Lecca Roberto Carlos Reyes, Oliveira Helio de, Poncioni Ivana Pereira de Almeida, Maranhão Maria Helian Nunes, Mendes Yluska Myrna Meneses Brandão E, Fernandes Roberto Men, Lima Raquel Barbosa de, Rabello Dácio de Lyra
机构信息
Ministério da Saúde, Secretaria de Vigilância em Saúde, Brasília-DF, Brasil.
出版信息
Epidemiol Serv Saude. 2016 Oct-Dec;25(4):701-712. doi: 10.5123/S1679-49742016000400004. Epub 2016 Sep 26.
OBJECTIVE
to describe the prevalence coefficients and characterize cases of microcephaly at birth in Brazil from 2000-2015.
METHODS
this is a descriptive study with data from the Information System on Live Births (Sinasc). The coefficients were calculated by region and characteristics of mothers and live births (LB).
RESULTS
the annual average number of microcephaly cases was 164 for the period 2000-2014, whilst in 2015, 1,608 cases were registered (54.6 cases per 100 thousand LB). Higher coefficients were observed among preterm babies (81.7; 95%CI 72.3;92.2), born from black-skinned (70.9; 95%CI 58.5;85.9) or to brown-skinned (71.5; 95%CI67.4;75.8) women, to women aged ≤19 (70.3; 95%CI 63.5;77.8) or ≥40 (62.1; 95%CI 46.6;82.6), with ≤3 years of study (73.4; 95%CI 58.2;92.4) and residents in the Northeast region (138.7; 95%CI 130.9;147.0).
CONCLUSION
the high number of microcephaly cases in 2015 reinforces the importance of Sinasc and the need to improve the surveillance of congenital anomalies.
目的
描述2000年至2015年巴西出生时小头畸形的患病率系数并对病例进行特征分析。
方法
这是一项利用活产信息系统（Sinasc）数据进行的描述性研究。系数按地区以及母亲和活产儿（LB）的特征进行计算。
结果
2000年至2014年期间小头畸形病例的年平均数量为164例，而在2015年，登记了1608例（每10万例活产儿中有54.6例）。在早产婴儿（81.7；95%置信区间72.3；92.2）、母亲为黑人（70.9；95%置信区间58.5；85.9）或棕色人种（71.5；95%置信区间67.4；75.8）、年龄≤19岁（70.3；95%置信区间63.5；77.8）或≥40岁（62.1；95%置信区间46.6；82.6）、受教育年限≤3年（73.4；95%置信区间58.2；92.4）以及居住在东北地区（138.7；95%置信区间130.9；147.0）的人群中观察到较高的系数。
结论
2015年小头畸形病例数量众多，这凸显了Sinasc的重要性以及加强先天性异常监测的必要性。
Zotero 插件