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诊断为精神分裂症谱系障碍且有暴力犯罪和无暴力犯罪的个体的社会心理功能的预测因素:Recoviwel 研究的结果。

Predictors of psychosocial functioning in people diagnosed with schizophrenia spectrum disorders that committed violent offences and in those that did not: Results of the Recoviwel study.

机构信息

Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; Department of Mental Health and Addiction Services, ASST Spedali Civili of Brescia, Brescia, Italy.

出版信息

Schizophr Res. 2024 Aug;270:112-120. doi: 10.1016/j.schres.2024.06.023. Epub 2024 Jun 18.

Abstract

Psychosocial functioning represents a core treatment target of Schizophrenia Spectrum Disorders (SSD), and several clinical and cognitive factors contribute to its impairment. However, determinants of psychosocial functioning in people living with SSD that committed violent offences remain to be more thoroughly explored. This study aims to separately assess and compare predictors of psychosocial functioning in people with SSD that did and that did not commit violent offences considering several clinical, cognitive and violence-related parameters. Fifty inmates convicted for violent crimes in a forensic psychiatry setting diagnosed with SSD (OP group) and fifty participants matched for age, gender, education, and diagnosis (Non-OP group) were included in the study. A higher risk of violent relapse as measured by HCR-20 clinical subscale scores (p < 0.002) and greater global clinical severity as measured by CGI-S scores (p = 0.023) emerged as individual predictors of worse psychosocial functioning, as measured by PSP scores, in the OP group. Greater global clinical severity (p < 0.001), worse performance in the processing speed domain as measured by the BACS Symbol Coding (p = 0.002) and TMT-A tests (p = 0.016) and higher levels of non-planning impulsivity as measured by BIS-11 scores (p < 0.001) emerged as individual predictors of worse psychosocial functioning in the Non-OP group. These results confirm that clinical severity impacts psychosocial functioning in all individuals diagnosed with SSD and suggest that while cognitive impairment clearly represents a determinant of worse functional outcomes in most patients, the risk of violent relapse is a specific predictor of worse psychosocial functioning in people with SSD that committed criminal offences.

摘要

心理社会功能是精神分裂症谱系障碍(SSD)的核心治疗目标,有几个临床和认知因素会导致其受损。然而,对于患有 SSD 且有暴力犯罪行为的人,其心理社会功能的决定因素仍需更深入地探讨。本研究旨在分别评估和比较患有 SSD 且有或没有暴力犯罪行为的人的心理社会功能的预测因素,考虑到几个临床、认知和与暴力相关的参数。该研究纳入了 50 名在法医精神病学环境中因暴力犯罪而被定罪的患有 SSD 的囚犯(OP 组)和 50 名年龄、性别、教育程度和诊断相匹配的参与者(非 OP 组)。OP 组中,HCR-20 临床子量表评分较高(p<0.002)和 CGI-S 评分较高(p=0.023),表明有更高的暴力复发风险,这是 PSP 评分较差的个体预测因素。非 OP 组中,总体临床严重程度更高(p<0.001)、BACS 符号编码(p=0.002)和 TMT-A 测试(p=0.016)中处理速度领域的表现更差、BIS-11 评分更高(p<0.001),表明非计划性冲动水平更高,这是 PSP 评分较差的个体预测因素。这些结果证实,临床严重程度会影响所有被诊断为 SSD 的个体的心理社会功能,并表明认知障碍显然是大多数患者功能结果较差的决定因素,而暴力复发的风险是有犯罪行为的 SSD 患者心理社会功能较差的特定预测因素。

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