Department of Psychological Sciences, Faculty of Health, Arts and Design, Swinburne University of Technology, Melbourne, Australia.
Department of Health Sciences and Biostatistics, Faculty of Health, Arts and Design, Swinburne University of Technology, Melbourne, Australia.
J Psychosom Res. 2024 Aug;183:111834. doi: 10.1016/j.jpsychores.2024.111834. Epub 2024 Jun 15.
To determine the prevalence and associations between anxiety/depression, and gastrointestinal (GI) symptoms across gastroparesis and functional dyspepsia.
Twenty adult studies were identified through systematic searches of three databases (PubMed, CINAHL and PsycINFO) in September 2023. Meta-analysis was performed to estimate the pooled prevalence rates of anxiety and depression across gastroparesis and functional dyspepsia, and to determine whether the associations of anxiety/depression and gastrointestinal (GI) symptoms differ in gastroparesis versus functional dyspepsia.
The overall pooled prevalence rate for anxiety was similar (χ(1) = 2.45, p = .12) in gastroparesis (49%) and functional dyspepsia (29%). The overall pooled prevalence rate for depression in gastroparesis (39%), and functional dyspepsia (32%) was also similar (χ(1) = 0.81, p = .37). No significant relationship between anxiety and GI symptoms (r = 0.11) or depression and GI symptoms (r = 0.16) was found in gastroparesis, whilst significant, though weak, positive relationships between anxiety and GI symptoms (r = 0.30) and depression and GI symptoms (r = 0.32) were found in functional dyspepsia. The association between GI symptoms and anxiety, but not depression, across gastroparesis and functional dyspepsia was found to be significant (χ(1) = 5.22, p = .02).
Contributing to ongoing debate as to whether gastroparesis and functional dyspepsia are interchangeable syndromes, this review found that anxiety and depression prevalence was similar in both conditions. Psychological assessment and the utilisation of effective and holistic care in both conditions is therefore warranted.
确定胃轻瘫和功能性消化不良患者焦虑/抑郁与胃肠道（GI）症状之间的患病率及其关联。
2023 年 9 月，通过系统检索三个数据库（PubMed、CINAHL 和 PsycINFO），共确定了 20 项成人研究。采用荟萃分析来估算胃轻瘫和功能性消化不良患者中焦虑和抑郁的总体患病率，并确定焦虑/抑郁与胃肠道（GI）症状之间的关联在胃轻瘫与功能性消化不良之间是否存在差异。
胃轻瘫（49%）和功能性消化不良（29%）患者中，焦虑的总体合并患病率相似（χ(1) = 2.45，p =.12）。胃轻瘫（39%）和功能性消化不良（32%）患者中，抑郁的总体合并患病率也相似（χ(1) = 0.81，p =.37）。在胃轻瘫中，焦虑与 GI 症状之间（r = 0.11）或抑郁与 GI 症状之间（r = 0.16）无显著关系，而在功能性消化不良中，焦虑与 GI 症状之间（r = 0.30）和抑郁与 GI 症状之间（r = 0.32）存在显著但较弱的正相关关系。在胃轻瘫和功能性消化不良中，GI 症状与焦虑之间的关联，但不是抑郁与 GI 症状之间的关联，被发现具有统计学意义（χ(1) = 5.22，p =.02）。
本研究对胃轻瘫和功能性消化不良是否可以互换的争议提供了新的见解，发现这两种疾病的焦虑和抑郁患病率相似。因此，有必要对这两种疾病进行心理评估，并采用有效和全面的护理方法。
