Cangiano A
Neuroscience. 1985 Apr;14(4):963-71. doi: 10.1016/0306-4522(85)90268-4.
A review about the neural regulation of the membrane distribution of muscle acetylcholine receptors is presented on the basis of author's and literature data. The main evidence in support of the role of nerve impulses and of chemical factors ("trophic" factors, acetylcholine, nerve breakdown products) as neural signals involved in the origin of denervation supersensitivity, is concisely described and evaluated. The contribution of breakdown products of the nerve, their interaction with muscle inactivity are illustrated and a unifying hypothesis on the neural control of extrajunctional and junctional acetylcholine receptors is presented.
基于作者本人及文献资料，本文对肌肉乙酰胆碱受体膜分布的神经调节进行了综述。简要描述并评估了支持神经冲动和化学因子（“营养”因子、乙酰胆碱、神经分解产物）作为参与去神经超敏反应起源的神经信号所起作用的主要证据。阐述了神经分解产物的作用及其与肌肉失活的相互作用，并提出了关于接头外和接头处乙酰胆碱受体神经控制的统一假说。
