Samsó Dies J M, Villa Badó J, Villalobos J, Iriarte J L, Ordeix R
Arzneimittelforschung. 1979;29(8a):1301-7.
The results obtained from a group of 36 patients with non-acute cerebral vascular disturbances of various forms were evaluated. The clinical course and additional examinations are reported: electroencephalography, visually evoked potentials and cerebral rheography for the assessment of different cerebral regions and an interhemispherical comparison. The determination of the data obtained by rheography can be applied to the whole patient group. All tests were carried out before treatment and after a period of treatment with 15-20 mg 10-methoxy-1,6-dimethyl-ergoline-8 beta-methanol-(5-bromonicotinate) (nicergoline, Sermion) administered daily p.o. On the basis of the therapeutic results conclusions can be drawn as to clinical improvement and EEG normalisation and visually evoked potentials. The changes in the amplitude and the changes in the systolic gradient recorded by the rheogramme as well as the tendency to correction of dyssymmetry can be described as the result of nicergoline on the cerebral vascular system, on the oxygen supply and on the metabolism of the brain tissue.
对一组36例患有各种形式非急性脑血管疾病的患者所获得的结果进行了评估。报告了临床病程及其他检查：脑电图、视觉诱发电位和脑血流图，用于评估不同脑区及半球间比较。脑血流图所获数据的测定可应用于整个患者组。所有检查均在治疗前以及每日口服15 - 20毫克10 - 甲氧基 - 1,6 - 二甲基 - 麦角灵 - 8β - 甲醇 -（5 - 溴烟酸酯）（尼麦角林，喜得镇）治疗一段时间后进行。根据治疗结果，可以得出关于临床改善、脑电图正常化和视觉诱发电位的结论。脑血流图记录的振幅变化、收缩期梯度变化以及不对称性校正趋势可描述为尼麦角林对脑血管系统、氧供应和脑组织代谢的作用结果。
