[直肠浅表活检中胆碱酯酶活性测定在先天性巨结肠症诊断中的价值]
[Value of the assay of cholinesterase activity in superficial biopsies of the rectum in the diagnosis of Hirschsprung's disease].
作者信息
Caussé E, Vaysse P, Guitard J, Thouvenot J P
出版信息
Pathol Biol (Paris). 1985 Feb;33(2):115-7.
PMID:3889781
Abstract
Cholinesterase activity have been estimated in rectal biopsies of 19 children with Hirschsprung's disease and 80 normal children. A high level of acetyl-cholinesterase is a strong argument for the diagnosis of aganglionosis. However the ratio acetylcholinesterase over butyrylcholinesterase seems to be a better sign allowing a right diagnosis in 99% of the cases.
摘要
已对19例患有先天性巨结肠症的儿童和80例正常儿童的直肠活检组织进行了胆碱酯酶活性评估。乙酰胆碱酯酶水平升高是诊断无神经节细胞症的有力依据。然而，乙酰胆碱酯酶与丁酰胆碱酯酶的比值似乎是一个更好的指标，在99%的病例中能做出正确诊断。
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