Hafström L, Persson B, Sundqvist K
Acta Physiol Scand. 1979 Jun;106(2):123-8. doi: 10.1111/j.1748-1716.1979.tb06380.x.
The cardiac output and regional blood flow have been simultaneously determined in the anesthetized rat by using the reference organ method. 99Tcm labelled dextran 15 micron microspheres were injected in the left ventricle while simultaneously an arterial reference sample was drawn at constant known rate. The values calculated regarding cardiac output agree well with previously recorded series. Regional organ blood flow in the rat is presented as ml . min-1 . g-1 tissue and values do agree with those reported by others. The results indicate that the reference organ method can be used in the rat for the study of cardiac output and regional blood flow.
采用参考器官法,在麻醉大鼠中同时测定心输出量和局部血流量。将99锝标记的15微米右旋糖酐微球注入左心室,同时以已知的恒定速率采集动脉参考样本。计算得出的心输出量值与先前记录的系列结果吻合良好。大鼠局部器官血流量以每克组织每分钟毫升数表示,其值与其他研究者报告的结果相符。结果表明,参考器官法可用于大鼠心输出量和局部血流量的研究。