Hirani Palak, Chandak Manoj, Agrawal Paridhi, Sarangi Swayangprabha, Suryawanshi Tejas, Jidewar Namrata, Naladkar Kapil
Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 May 20;16(5):e60691. doi: 10.7759/cureus.60691. eCollection 2024 May.
This article provides an overview of a biologically based method for restoring damaged tooth structures and pulp tissues known as regenerative endodontics. It explores the concept of regenerative endodontics, its tissue engineering approach, and its application in maintaining vitality. The article discusses the significance of the factors affecting growth, scaffolds, and stem cells being the three tissue engineering components involved in the regeneration of pulp tissues. It also delves into the classification of scaffolds and the role of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) as biological scaffolds. The methodology section details the search process for relevant studies, and the review section presents research findings associated with PRF and its application in regeneration and repair of tissue. The article concludes by highlighting the potential of advanced PRF and injectable PRF in regenerative endodontics, with a focus on their impact on tissue regeneration and healing.
本文概述了一种基于生物学的修复受损牙齿结构和牙髓组织的方法,即再生牙髓治疗学。它探讨了再生牙髓治疗学的概念、其组织工程方法及其在维持活力方面的应用。本文讨论了影响生长的因素、支架和干细胞这三个参与牙髓组织再生的组织工程组成部分的重要性。它还深入探讨了支架的分类以及富含血小板纤维蛋白(PRF)和富含血小板血浆(PRP)作为生物支架的作用。方法部分详细介绍了相关研究的搜索过程,综述部分展示了与PRF及其在组织再生和修复中的应用相关的研究结果。本文最后强调了先进PRF和可注射PRF在再生牙髓治疗学中的潜力,重点是它们对组织再生和愈合的影响。