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血小板力量：用支架重振牙髓病学。

Platelet Power: Revitalizing Endodontics With Scaffolds.

作者信息

Hirani Palak, Chandak Manoj, Agrawal Paridhi, Sarangi Swayangprabha, Suryawanshi Tejas, Jidewar Namrata, Naladkar Kapil

机构信息

Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2024 May 20;16(5):e60691. doi: 10.7759/cureus.60691. eCollection 2024 May.

DOI:10.7759/cureus.60691
PMID:38899240
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11186587/
Abstract

This article provides an overview of a biologically based method for restoring damaged tooth structures and pulp tissues known as regenerative endodontics. It explores the concept of regenerative endodontics, its tissue engineering approach, and its application in maintaining vitality. The article discusses the significance of the factors affecting growth, scaffolds, and stem cells being the three tissue engineering components involved in the regeneration of pulp tissues. It also delves into the classification of scaffolds and the role of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) as biological scaffolds. The methodology section details the search process for relevant studies, and the review section presents research findings associated with PRF and its application in regeneration and repair of tissue. The article concludes by highlighting the potential of advanced PRF and injectable PRF in regenerative endodontics, with a focus on their impact on tissue regeneration and healing.

摘要

本文概述了一种基于生物学的修复受损牙齿结构和牙髓组织的方法，即再生牙髓治疗学。它探讨了再生牙髓治疗学的概念、其组织工程方法及其在维持活力方面的应用。本文讨论了影响生长的因素、支架和干细胞这三个参与牙髓组织再生的组织工程组成部分的重要性。它还深入探讨了支架的分类以及富含血小板纤维蛋白（PRF）和富含血小板血浆（PRP）作为生物支架的作用。方法部分详细介绍了相关研究的搜索过程，综述部分展示了与PRF及其在组织再生和修复中的应用相关的研究结果。本文最后强调了先进PRF和可注射PRF在再生牙髓治疗学中的潜力，重点是它们对组织再生和愈合的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/10f4394ca973/cureus-0016-00000060691-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/d8f6bece863c/cureus-0016-00000060691-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/afd7e9338176/cureus-0016-00000060691-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/9f3cd7152f75/cureus-0016-00000060691-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/b30d55ff75a4/cureus-0016-00000060691-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/10f4394ca973/cureus-0016-00000060691-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/d8f6bece863c/cureus-0016-00000060691-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/afd7e9338176/cureus-0016-00000060691-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/9f3cd7152f75/cureus-0016-00000060691-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/b30d55ff75a4/cureus-0016-00000060691-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f12b/11186587/10f4394ca973/cureus-0016-00000060691-i05.jpg

相似文献

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本文引用的文献

1
Pioneering Periapical Healing: The Novel Synergy of Mineral Trioxide Aggregate and Injectable Platelet-Rich Fibrin.开创性的根尖周愈合：三氧化矿物凝聚体与可注射富血小板纤维蛋白的新型协同作用
Cureus. 2023 Oct 1;15(10):e46341. doi: 10.7759/cureus.46341. eCollection 2023 Oct.
2
Next generation antibacterial strategies for regenerative endodontic procedures: A scoping review.再生牙髓治疗的下一代抗菌策略：范围综述。
Int Endod J. 2024 Jul;57(7):804-814. doi: 10.1111/iej.13958. Epub 2023 Jul 31.
3
The efficacy of concentrated growth factor and platelet-rich fibrin as scaffolds in regenerative endodontic treatment applied to immature permanent teeth: a retrospective study.
浓缩生长因子和富血小板纤维蛋白作为支架在再生性牙髓治疗应用于未成熟恒牙中的疗效：一项回顾性研究。
BMC Oral Health. 2023 Jul 14;23(1):482. doi: 10.1186/s12903-023-03164-y.
4
Comparative Evaluation of Platelet-rich Fibrin and Concentrated Growth Factor as Scaffolds in Regenerative Endodontic Procedure: A Randomized Controlled Clinical Trial.富血小板纤维蛋白和浓缩生长因子作为再生牙髓治疗中支架的比较评价：一项随机对照临床试验。
J Contemp Dent Pract. 2022 Dec 1;23(12):1211-1217. doi: 10.5005/jp-journals-10024-3443.
5
Regenerative Endodontics by Cell Homing: A Review of Recent Clinical trials.牙髓再生学中的细胞归巢：近期临床试验的综述。
J Endod. 2023 Jan;49(1):4-17. doi: 10.1016/j.joen.2022.09.008. Epub 2022 Oct 18.
6
Platelet-Rich Fibrin Used in Regenerative Endodontics and Dentistry: Current Uses, Limitations, and Future Recommendations for Application.富血小板纤维蛋白在再生牙髓病学和牙科中的应用：当前用途、局限性及未来应用建议
Int J Dent. 2021 Dec 15;2021:4514598. doi: 10.1155/2021/4514598. eCollection 2021.
7
Lyophilised Platelet-Rich Fibrin: Physical and Biological Characterisation.冻干富血小板纤维蛋白：物理和生物学特性。
Molecules. 2021 Nov 25;26(23):7131. doi: 10.3390/molecules26237131.
8
Platelet-rich fibrin: Basics of biological actions and protocol modifications.富血小板纤维蛋白：生物学作用基础及方案改良
Open Med (Wars). 2021 Mar 22;16(1):446-454. doi: 10.1515/med-2021-0259. eCollection 2021.
9
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Exp Ther Med. 2021 Mar;21(3):226. doi: 10.3892/etm.2021.9657. Epub 2021 Jan 18.
10
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Aust Endod J. 2021 Aug;47(2):157-162. doi: 10.1111/aej.12438. Epub 2020 Sep 14.