Nathan R S, Perel J M, McCarthy T, Jarrett D B
Psychoneuroendocrinology. 1985;10(1):71-6. doi: 10.1016/0306-4530(85)90040-x.
Prolactin (PRL) responses to haloperidol were investigated at 0900 and 1800 h in six young healthy men under basal conditions and after benztropine mesylate administration. Haloperidol administration induced significantly higher PRL release during the evening compared to the morning. The anticholinergic drug, benztropine, potentiated the PRL responses to haloperidol both in the morning and in the evening. The possible mechanisms of these findings are discussed.
在基础条件下以及给予甲磺酸苯扎托品后，于上午09:00和下午18:00对6名年轻健康男性进行了催乳素（PRL）对氟哌啶醇反应的研究。与早晨相比，晚上给予氟哌啶醇诱导的PRL释放显著更高。抗胆碱能药物甲磺酸苯扎托品在早晨和晚上均增强了PRL对氟哌啶醇的反应。文中讨论了这些发现的可能机制。
