Florholmen J, Revhaug A, Burhol P G, Giercksky K E, Olsen R L
Scand J Gastroenterol. 1985 Apr;20(3):279-84. doi: 10.3109/00365528509091650.
In six pigs intravenous administration of Escherichia coli endotoxin caused septic shock and a significant increase in serum cationic trypsin-like immunoreactivity (CTLI), with activation of cationic trypsinogen to trypsin and formation of complexes between cationic trypsin, on the one hand, and alpha 2-macroglobulin and alpha 1-antitrypsin, on the other, compatible with acute pancreatitis. In contrast, intraduodenal infusion of E. coli endotoxin to seven other pigs was without effect on the general circulation and on the serum CTLI.
在六头猪中，静脉注射大肠杆菌内毒素导致脓毒性休克，并使血清阳离子胰蛋白酶样免疫反应性（CTLI）显著增加，同时阳离子胰蛋白酶原被激活为胰蛋白酶，且一方面阳离子胰蛋白酶与另一方面的α2-巨球蛋白和α1-抗胰蛋白酶之间形成复合物，这与急性胰腺炎相符。相比之下，向另外七头猪十二指肠内注入大肠杆菌内毒素对全身循环和血清CTLI没有影响。
