Broghamer W L, Richardson M E, Faurest S, Parker J E
Acta Cytol. 1985 May-Jun;29(3):274-8.
An immunoperoxidase staining technique was employed in an effort to demonstrate prostatic acid phosphatase in sections of the effusion cell blocks in a retrospective investigation of the incidence of malignant prostatic cells in body cavity effusions in 33 patients with histologically confirmed prostatic cancer. An attempt was also made to identify the prostate as a possible anatomic site of origin in 26 patients with an unknown primary but with cytologically positive fluids. Neoplastic cells were identified in the effusion specimens in 21.2% of the patients with confirmed prostatic cancer; the sources, however, were either primary or metastatic carcinomas of nonprostatic origin. None of the cytologic specimens in this study demonstrated a positive prostate-specific acid phosphatase staining reaction, as did the prostatic metastases to the lungs used as controls.
采用免疫过氧化物酶染色技术，对33例经组织学确诊为前列腺癌患者体腔积液中恶性前列腺细胞的发生率进行回顾性研究，以在积液细胞块切片中显示前列腺酸性磷酸酶。还对26例原发灶不明但细胞学检查积液呈阳性的患者进行了研究，试图确定前列腺是否为可能的解剖学起源部位。在确诊为前列腺癌的患者中，21.2%的积液标本中发现了肿瘤细胞；然而，其来源为非前列腺起源的原发性或转移性癌。本研究中没有一份细胞学标本显示出前列腺特异性酸性磷酸酶染色反应呈阳性，而用作对照的肺前列腺转移灶则呈阳性。
