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SARS-CoV-2 大流行和封锁措施对台湾微生物性角膜炎的影响。

Impact of SARS-CoV-2 pandemic and lockdown measures on microbial keratitis in Taiwan.

机构信息

College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.

Department of Ophthalmology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, 70101, Taiwan.

出版信息

Int Ophthalmol. 2024 Jun 21;44(1):238. doi: 10.1007/s10792-024-03200-y.

Abstract

PURPOSE

This study aimed to evaluate how the SARS-CoV-2 pandemic and associated lockdown measures influenced microbial keratitis in Taiwan by comparing demographic data, predisposing factors, pathogen profiles, and treatment outcomes in 2019 and 2020.

METHODS

Data from patients diagnosed with microbial keratitis at National Chung Kung University Hospital between January 2019 and December 2020 were examined, focusing on patient demographics, predisposing factors, isolated pathogens, antibiotic usage, and clinical progress.

RESULTS

No significant differences were found in patient sex, laterality, or average age between the two years. Predisposing factors, such as contact lens use and chronic ocular/systemic disorders, remained unchanged. While fungal isolates slightly increased during the lockdown, bacterial isolates remained consistent. Medical treatment effectiveness, treatment strategies, and antibiotic susceptibility for common bacteria showed no significant alterations.

CONCLUSION

Despite the challenges posed by the SARS-CoV-2 pandemic and lockdown measures, this study revealed minimal changes in microbial keratitis trends in Taiwan. This highlights the importance of maintaining access to medical care during crises and offers insights into potential treatment strategies for patients facing difficulties in receiving timely care. Further research should investigate the pandemic's impact on healthcare access and patient outcomes in various populations and regions.

摘要

目的

本研究旨在通过比较 2019 年和 2020 年的人口统计学数据、致病因素、病原体谱和治疗结果,评估 SARS-CoV-2 大流行及相关封锁措施对台湾地区微生物性角膜炎的影响。

方法

研究分析了 2019 年 1 月至 2020 年 12 月期间在国立成功大学医院诊断为微生物性角膜炎的患者的数据,重点关注患者的人口统计学数据、致病因素、分离病原体、抗生素使用情况和临床进展。

结果

两年间,患者的性别、眼别和平均年龄均无显著差异。接触镜使用和慢性眼部/系统疾病等致病因素保持不变。虽然在封锁期间真菌分离物略有增加,但细菌分离物保持一致。常见细菌的医疗治疗效果、治疗策略和抗生素敏感性没有显著变化。

结论

尽管 SARS-CoV-2 大流行和封锁措施带来了挑战,但本研究显示台湾地区微生物性角膜炎的趋势变化很小。这突显了在危机期间维持医疗保健可及性的重要性,并为面临难以及时获得治疗的患者提供了潜在的治疗策略。应进一步研究大流行对不同人群和地区的医疗保健可及性和患者结局的影响。

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