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Carbon monoxide licensing of MSCs enhances their efficacy through autophagy-mediated miRNA mechanisms.

作者信息

Dunbar Hazel, Hawthorne Ian J, English Karen

机构信息

Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.

Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.

出版信息

Mol Ther. 2024 Jul 3;32(7):2047-2049. doi: 10.1016/j.ymthe.2024.06.008. Epub 2024 Jun 20.

DOI:10.1016/j.ymthe.2024.06.008
PMID:38906151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11286800/
Abstract
摘要

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本文引用的文献

1
Carbon monoxide-induced autophagy enhances human mesenchymal stromal cell function via paracrine actions in murine polymicrobial sepsis.一氧化碳诱导的自噬通过旁分泌作用增强人骨髓间充质干细胞在鼠脓毒症中的功能。
Mol Ther. 2024 Jul 3;32(7):2232-2247. doi: 10.1016/j.ymthe.2024.05.018. Epub 2024 May 11.
2
The MSC-EV-microRNAome: A Perspective on Therapeutic Mechanisms of Action in Sepsis and ARDS.MSC-EV 微小 RNA 组学:脓毒症和 ARDS 治疗作用机制的新视角。
Cells. 2024 Jan 9;13(2):122. doi: 10.3390/cells13020122.
3
Human macrophage migration inhibitory factor potentiates mesenchymal stromal cell efficacy in a clinically relevant model of allergic asthma.人巨噬细胞移动抑制因子增强间充质基质细胞在变应性哮喘临床相关模型中的疗效。
Mol Ther. 2023 Nov 1;31(11):3243-3258. doi: 10.1016/j.ymthe.2023.09.013. Epub 2023 Sep 20.
4
Therapeutic potential of mesenchymal stromal/stem cells in critical-care patients with systemic inflammatory response syndrome.间充质基质/干细胞在全身炎症反应综合征危重症患者中的治疗潜力。
Clin Transl Med. 2023 Jan;13(1):e1163. doi: 10.1002/ctm2.1163.
5
The Effect of Mesenchymal Stromal Cells on the Mortality of Patients with Sepsis and Septic Shock: A Promising Therapy.间充质基质细胞对脓毒症和脓毒性休克患者死亡率的影响:一种有前景的治疗方法。
Emerg Med Int. 2022 Jun 24;2022:9222379. doi: 10.1155/2022/9222379. eCollection 2022.
6
The Inflammatory Lung Microenvironment; a Key Mediator in MSC Licensing.炎症性肺微环境;MSC 许可的关键介质。
Cells. 2021 Nov 2;10(11):2982. doi: 10.3390/cells10112982.
7
Cyclosporine A and IFNγ licencing enhances human mesenchymal stromal cell potency in a humanised mouse model of acute graft versus host disease.环孢素 A 和 IFNγ 许可增强了人基质间充质干细胞在急性移植物抗宿主病的人源化小鼠模型中的效力。
Stem Cell Res Ther. 2021 Apr 14;12(1):238. doi: 10.1186/s13287-021-02309-6.
8
Mesenchymal stromal cell therapy: progress in manufacturing and assessments of potency.间充质基质细胞治疗:制造和效力评估的进展。
Cytotherapy. 2019 Mar;21(3):289-306. doi: 10.1016/j.jcyt.2018.10.014. Epub 2018 Dec 6.
9
Mitochondria and carbon monoxide: cytoprotection and control of cell metabolism - a role for Ca(2+) ?线粒体与一氧化碳:细胞保护及细胞代谢调控——钙离子的作用?
J Physiol. 2016 Aug 1;594(15):4131-8. doi: 10.1113/JP270955. Epub 2015 Dec 7.
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Assessing available information on the burden of sepsis: global estimates of incidence, prevalence and mortality.评估脓毒症负担的现有信息:发病率、患病率和死亡率的全球估计数。
J Glob Health. 2012 Jun;2(1):010404. doi: 10.7189/jogh.02.010404.