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Neuroimaging biomarkers in the biological definition of Parkinson's disease and dementia with Lewy bodies - EANM position on current state, unmet needs and future perspectives.

作者信息

Brendel Matthias, Guedj Eric, Yakushev Igor, Morbelli Silvia, Höglinger Günter U, Tolboom Nelleke, Verger Antoine, Albert Nathalie L, Cecchin Diego, Fernandez Pablo Aguiar, Fraioli Francesco, Traub-Weidinger Tatjana, Van Weehaeghe Donatienne, Barthel Henryk

机构信息

Department of Nuclear Medicine, LMU Hospital, Ludwig-Maximilians-University of Munich, Marchioninstraße 15, 81377, Munich, Germany.

German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

出版信息

Eur J Nucl Med Mol Imaging. 2024 Oct;51(12):3496-3500. doi: 10.1007/s00259-024-06803-w.

DOI:10.1007/s00259-024-06803-w
PMID:
38907856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11445360/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7e4/11445360/7359d1eac22f/259_2024_6803_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7e4/11445360/7359d1eac22f/259_2024_6803_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7e4/11445360/7359d1eac22f/259_2024_6803_Fig1_HTML.jpg

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Lancet Neurol. 2024 Feb;23(2):191-204. doi: 10.1016/S1474-4422(23)00404-0.
2
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research.神经元α-突触核蛋白病的生物学定义：建立研究用综合分期系统。
Lancet Neurol. 2024 Feb;23(2):178-190. doi: 10.1016/S1474-4422(23)00405-2.
3
α-Synuclein Seeding Amplification Assay: A Breakthrough in Diagnosing Parkinson Disease?
α-突触核蛋白种子扩增检测：帕金森病诊断的一项突破？
J Nucl Med. 2024 Feb 1;65(2):174-175. doi: 10.2967/jnumed.123.266191.
4
The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases.α-突触核蛋白 PET 示踪剂[18F]ACI-12589 可将多系统萎缩与其他神经退行性疾病区分开来。
Nat Commun. 2023 Oct 27;14(1):6750. doi: 10.1038/s41467-023-42305-3.
5
Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies.用于成像突触核蛋白病的α-突触核蛋白正电子发射断层扫描示踪剂的开发。
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