Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Department of Gynecology, School of Medicine, Reproductive Health Research Center, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Clin Nutr ESPEN. 2024 Oct;63:31-45. doi: 10.1016/j.clnesp.2024.05.011. Epub 2024 Jun 8.
One's neurobehavioural and mental health are built during the exact and complex process of brain development. It is thought that fetal development is where neuropsychiatric disorders first emerged. Behavioural patterns can change as a result of neuropsychiatric illnesses. The incidence is rising quickly; nevertheless, providing exceptional care remains a significant challenge for families and healthcare systems. It has been demonstrated that one of the main factors causing the transmission of these diseases is maternal exposure. Through physiologic pathways, maternal health and intrauterine exposures can affect brain development. Our attention has been focused on epigenetic factors, particularly in the gestational environment, which may be responsible for human neurodegenerative diseases since our main mental development occurs during the nine months of intrauterine life. After thoroughly searching numerous databases, this study examined the effect of fat-soluble vitamins, water-soluble vitamins, and minerals and their maternal-level effect on brain development.
一个人的神经行为和心理健康是在大脑发育的确切和复杂过程中建立的。人们认为神经精神疾病最初出现在胎儿发育时期。行为模式会因神经精神疾病而改变。尽管发病率迅速上升，但为家庭和医疗保健系统提供特殊护理仍然是一个重大挑战。已经证明，导致这些疾病传播的主要因素之一是母体暴露。通过生理途径，母体健康和宫内暴露会影响大脑发育。由于我们的主要精神发育发生在宫内生命的九个月内，因此我们一直关注可能导致人类神经退行性疾病的表观遗传因素，特别是在妊娠期环境中。在彻底搜索了多个数据库后，本研究检查了脂溶性维生素、水溶性维生素和矿物质及其对大脑发育的母体水平效应。
