Kikina Anna Yu, Matrosova Mariia S, Gorbacheva Elena Yu, Gogichaeva Ksenia K, Toniyan Konstantin A, Boyarintsev Valery V, Kotov Oleg V, Ogneva Irina V
Gagarin Research and Test Cosmonaut Training Center, 141160, Star City, Moscow Region, Russia.
Radiology Department, European Medical Center, 129090, Moscow, Russia.
NPJ Microgravity. 2024 Jun 22;10(1):70. doi: 10.1038/s41526-024-00413-4.
The participation of women in space programs of increasing flight duration requires research of their reproductive system from the perspective of subsequent childbearing and healthy aging. For the first time, we present hormonal and structural data on the dynamics of recovery after a 157-day space flight in a woman of reproductive age. There were no clinically significant changes in the reproductive system, but detailed analysis shows that weightlessness leads to an increase in the proportion of early antral follicles and granulosa cells in large antral follicles. Returning to Earth's gravity reduces the number and diameter of early antral follicles.
女性参与飞行时长不断增加的太空计划，需要从后续生育及健康衰老的角度对其生殖系统进行研究。我们首次呈现了一名育龄女性在经历157天太空飞行后恢复动态的激素和结构数据。生殖系统未出现具有临床意义的变化，但详细分析表明，失重会导致早期窦卵泡比例增加以及大的窦卵泡中颗粒细胞增多。回到地球引力环境后，早期窦卵泡的数量和直径会减少。
