Ito Satoki, Tamura Takuya, Ishihara Yuji, Ito Haruka, Noda Tomoko, Ito Hiroki
Department of Neurology, Ichinomiya Municipal Hospital.
Rinsho Shinkeigaku. 2024 Jul 27;64(7):490-495. doi: 10.5692/clinicalneurol.cn-001978. Epub 2024 Jun 22.
A 43-year-old man was admitted to our department due to fever and headache. The cerebrospinal fluid analysis confirmed bacterial meningitis. Campylobacter species were isolated from blood cultures on the third day of admission. The patient was treated with meropenem (MEPM) and discharged on the 17th day. However, he experienced a recurrence of meningitis and was readmitted on the 68th day, initiating MEPM therapy. Campylobacter fetus was isolated from cerebrospinal fluid cultures on the 74th day. MEPM was continued until the 81st day, followed by one month of minocycline (MINO) therapy. The patient had an uneventful recovery without further recurrence. This case highlights the potential for recurrence of Campylobacter fetus meningitis approximately two months after the resolution of the initial infection. In addition to carbapenem therapy for at least two weeks, the adjunctive administration of MINO may be beneficial.
一名43岁男性因发热和头痛入院。脑脊液分析确诊为细菌性脑膜炎。入院第三天血培养分离出弯曲杆菌属。患者接受美罗培南（MEPM）治疗，于第17天出院。然而，他脑膜炎复发，于第68天再次入院，开始美罗培南治疗。第74天脑脊液培养分离出胎儿弯曲杆菌。美罗培南持续使用至第81天，随后进行了一个月的米诺环素（MINO）治疗。患者康复顺利，未再复发。该病例突出了胎儿弯曲杆菌脑膜炎在初始感染消退后约两个月复发的可能性。除了至少两周的碳青霉烯类治疗外，辅助使用米诺环素可能有益。
