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酷似恶性肿瘤的卵巢硬化性间质瘤:病例系列及文献综述

Ovarian sclerosing stromal tumor mimicking malignancy: case series and literature review.

作者信息

Skuk Eva, Cvjetićanin Branko, Pirš Boštjan, Belcijan Neža Lebič, Jakimovska Marina

机构信息

Division of Gynaecology and Obstetrics, Department of Gynaecology, University Medical Centre Ljubljana, Zaloška 7, 1000, Ljubljana, Slovenia.

Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000, Ljubljana, Slovenia.

出版信息

Arch Gynecol Obstet. 2024 Aug;310(2):1171-1177. doi: 10.1007/s00404-024-07520-3. Epub 2024 Jun 24.

DOI:10.1007/s00404-024-07520-3
PMID:38910143
Abstract

BACKGROUND

Sclerosing stromal tumors (SST) are rare ovarian neoplasms that often appear as solid unilateral tumors of the ovary with no specific clinical or radiological presentation. The definitive treatment is surgical removal.

CASE PRESENTATION

Our article presents four cases of female patients with sclerosing stromal ovarian tumor with clinical characteristics mimicking malignant ovarian lesions. Interestingly, two of our cases had elevated levels of inhibin B. All patients were treated with surgery (oophorectomy) and had no disease recurrence.

CONCLUSION

Tumors' macroscopic features are usually non-specific and often suggestive of possible malignancy, therefore diagnosis is always based on histopathological report.

摘要

背景

硬化性间质瘤(SST)是罕见的卵巢肿瘤,常表现为卵巢实性单侧肿瘤,无特定的临床或影像学表现。 definitive治疗方法是手术切除。

病例报告

我们的文章介绍了4例硬化性间质卵巢肿瘤女性患者,其临床特征类似恶性卵巢病变。有趣的是,我们的2例患者抑制素B水平升高。所有患者均接受了手术治疗(卵巢切除术),且无疾病复发。

结论

肿瘤的宏观特征通常不具有特异性,常提示可能为恶性,因此诊断始终基于组织病理学报告。

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本文引用的文献

1
A rare case of sclerosing stromal tumor of the ovary presenting in pregnancy: a case report and review of the literature.罕见妊娠合并卵巢硬化性间质瘤 1 例报告并文献复习
J Int Med Res. 2023 Feb;51(2):3000605231152385. doi: 10.1177/03000605231152385.
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A Rare Ovarian Tumor: The Sclerosing Stromal You Do Not Expect-A Case Series in the Adolescent Population and a Literature Review.一种罕见的卵巢肿瘤:硬化性间质瘤——青少年人群中的病例系列及文献综述
Pediatr Rep. 2023 Jan 5;15(1):20-32. doi: 10.3390/pediatric15010004.
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Sclerosing Stromal Tumor of the Ovary Presenting as Meigs Syndrome During Childhood.
儿童期表现为梅格斯综合征的卵巢硬化性间质瘤。
Cureus. 2022 Nov 16;14(11):e31562. doi: 10.7759/cureus.31562. eCollection 2022 Nov.
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Sclerosing stromal tumor of the ovary: a case series and review of literature.卵巢硬化性间质瘤:病例系列及文献复习
BJR Case Rep. 2021 Dec 3;8(2):20210155. doi: 10.1259/bjrcr.20210155. eCollection 2022 Mar 10.
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Sclerosing stromal tumour: a clinicopathological study of 100 cases of a distinctive benign ovarian stromal tumour typically occurring in the young.硬化性间质瘤:100例典型发生于年轻女性的独特良性卵巢间质瘤的临床病理研究
Histopathology. 2022 Jan;80(2):360-368. doi: 10.1111/his.14554. Epub 2021 Nov 16.
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Ovarian sex cord stromal tumours: analysis of the clinical and sonographic characteristics of different histopathologic subtypes.卵巢性索间质肿瘤:不同组织病理学亚型的临床和超声特征分析。
J Ovarian Res. 2021 Apr 17;14(1):53. doi: 10.1186/s13048-021-00805-0.
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Sclerosing stromal tumor of the ovary with masculinization, Meig's syndrome and CA125 elevation in an adolescent girl: A case report.一名青春期女孩患伴有男性化、梅格斯综合征及CA125升高的卵巢硬化性间质瘤:病例报告
World J Clin Cases. 2020 Dec 26;8(24):6364-6372. doi: 10.12998/wjcc.v8.i24.6364.
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ESGO-SIOPE guidelines for the management of adolescents and young adults with non-epithelial ovarian cancers.ESGO-SIOPE 指南:青少年和年轻女性非上皮性卵巢癌的管理。
Lancet Oncol. 2020 Jul;21(7):e360-e368. doi: 10.1016/S1470-2045(20)30091-7.
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Sclerosing stromal tumor of the ovary in a postmenopausal woman with estrogen excess: A case report.一名绝经后雌激素过多女性的卵巢硬化性间质瘤:病例报告
Medicine (Baltimore). 2019 Nov;98(47):e18171. doi: 10.1097/MD.0000000000018171.
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