Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Department of Obstetrics and Gynecology, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Science, Beijing, China.
J Int Med Res. 2023 Feb;51(2):3000605231152385. doi: 10.1177/03000605231152385.
Sclerosing stromal tumor of the ovary (SSTO) is a rare benign neoplasm of the ovary, accounting for about 6% of all sex cord stromal ovarian tumors. Only 17 cases of SSTO occurring during pregnancy have been reported to date. We report a case of SSTO occurring during pregnancy and review the existing literature. A 32-year-old pregnant woman was found to have a 10-cm solid mass in the right adnexa, and a large volume of ascites fluid was detected by ultrasound examination in the second trimester. The patient underwent abdominal puncture to relieve her symptoms in the second trimester, and a partial right oophorectomy and cesarean section were performed at 39 weeks of gestation. Final pathology confirmed the diagnosis of SSTO. Both the mother and baby were well at 6 months of postpartum follow-up. Clinical symptoms, and hormone and imaging examinations are all helpful in making a differential diagnosis of SSTO, but the unique histopathological and immunohistochemistry findings remain the main diagnostic features. Pregnant women with SSTO usually undergo enucleation or unilateral oophorectomy, which generally does not have adverse pregnancy outcomes.
卵巢硬化性间质瘤(SSTO)是一种罕见的卵巢良性肿瘤,约占所有性索间质卵巢肿瘤的 6%。迄今为止,仅报道了 17 例妊娠期间发生的 SSTO 病例。我们报告了 1 例妊娠期间发生的 SSTO 病例,并复习了现有文献。一位 32 岁的孕妇在妊娠中期被发现右侧附件有一个 10cm 的实性肿块,超声检查发现大量腹水。患者在妊娠中期接受了腹部穿刺以缓解症状,并在 39 周时进行了部分右侧卵巢切除术和剖宫产术。最终病理证实诊断为 SSTO。母婴在产后 6 个月随访时均状况良好。临床症状、激素和影像学检查均有助于对 SSTO 进行鉴别诊断,但独特的组织病理学和免疫组织化学表现仍然是主要的诊断特征。妊娠期间的 SSTO 患者通常行肿瘤剔除术或单侧卵巢切除术,通常不会对妊娠结局产生不良影响。