Obstetrics and Gynecology Clinic, Tuzla State Hospital, Istanbul, Turkey.
Obstetrics and Gynecology Department, Marmara University School of Medicine, Istanbul, Turkey.
Gynecol Endocrinol. 2024 Dec;40(1):2362249. doi: 10.1080/09513590.2024.2362249. Epub 2024 Jun 24.
To investigate the association between female sexual function and metabolic features among women with polycystic ovary syndrome (PCOS) during reproductive age.
This was a cross-sectional study in which 288 women with PCOS and 180 women without PCOS between the ages of 20 and 40 years were evaluated. All women had serum total testosterone, androstenedione, DHEA-S, fasting glucose, total cholesterol, HDL-C, LDL-C, and triglyceride levels analyzed. The McCoy Female Sexual Questionnaire (MFSQ) was applied to all studied women. Exploratory factor analysis and reliability analysis were done after data collection. The factor loadings of MFSQ domains were compared between women with PCOS and controls.
Average factor loadings of the MFSQ sexuality domain and MFSQ sexual partner domain were significantly lower in the PCOS group when compared to controls. There was no correlation between the two sexual function domains of the MFSQ and the PCOS features either in the PCOS group or the controls.
PCOS is a heterogeneous disease with different metabolic components, such as insulin resistance, obesity, and hyperandrogenism. Although sexual function among women with PCOS was lower than controls, no differences were found in metabolic features of the PCOS and non-PCOS groups with relation to sexual function determined by the MFSQ.
探讨生育期多囊卵巢综合征(PCOS)女性的性功能与代谢特征之间的关系。
这是一项横断面研究,共纳入 288 例年龄在 20 至 40 岁之间的 PCOS 女性和 180 例非 PCOS 女性。所有女性均检测血清总睾酮、雄烯二酮、硫酸脱氢表雄酮、空腹血糖、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和甘油三酯水平。对所有研究对象应用 McCoy 女性性功能问卷(MFSQ)进行评估。数据收集后进行探索性因子分析和信度分析。比较 PCOS 组与对照组 MFSQ 各领域的因子负荷。
与对照组相比,PCOS 组 MFSQ 性行为领域和 MFSQ 性伴侣领域的平均因子负荷明显较低。无论是在 PCOS 组还是在对照组中,MFSQ 的两个性功能领域与 PCOS 特征均无相关性。
PCOS 是一种具有不同代谢成分(如胰岛素抵抗、肥胖和高雄激素血症)的异质性疾病。尽管 PCOS 女性的性功能低于对照组,但在 MFSQ 确定的与性功能相关的代谢特征方面,PCOS 组与非 PCOS 组之间并无差异。