Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China.
J Orthop Surg Res. 2024 Jun 24;19(1):374. doi: 10.1186/s13018-024-04862-1.
The coronavirus disease 2019 (COVID-19) rapidly spreads worldwide and causes more suffering. The relation about the aggravation of inguinal pain and COVID-19 was unclear in patients with total hip arthroplasty (THA). This study aimed to evaluate the risk of groin pain aggravation in short-term THA patients after COVID-19.
Between 2020 and 2022, 129 patients with THA who were affected COVID-19 were enrolled. A short-standardized questionnaire was administered during follow-up to inquire about the aggravation of groin ache before and after SARS-COV-2 affection. Furthermore, we evaluated the potential association between the presence of increased pain and various factors, including age, gender, body mass index, diagnosis, and length of hospital stay.
The case-crossover study revealed an increased risk of inguinal soreness aggravation when comparing 8 weeks after COVID-19 with 12 weeks before COVID-19 (Relative risk [RR], 9.5; 95% Confidence intervals [CI], 2.259-39.954). For COVID-19 positive patients, multivariate analysis showed length of stay was an independent factor significantly associated with increased risk of aggravation of groin pain (Odds ratio [OR], 1.26; 95%CI, 1.03-1.55, p = 0.027).
This study confirms the association between COVID-19 and the exacerbation of soreness in the groin region in THA patients and extended length of stay is a possible contributing factor. This study expands the current literature by investigating the risk of aggravation of inguinal pain in patients with THA after COVID-19, providing valuable insights into postoperative outcomes in this specific population. Trial registration This retrospective study was approved by the Institutional Review Board of Shanghai general hospital (No.2023-264).
2019 年冠状病毒病（COVID-19）在全球迅速传播，造成更多痛苦。在接受全髋关节置换术（THA）的患者中，腹股沟疼痛加重与 COVID-19 之间的关系尚不清楚。本研究旨在评估 COVID-19 后短期 THA 患者腹股沟疼痛加重的风险。
2020 年至 2022 年间，共纳入 129 例感染 COVID-19 的 THA 患者。在随访期间，通过短标准化问卷询问 SARS-COV-2 感染前后腹股沟疼痛加重的情况。此外，我们评估了疼痛增加的存在与各种因素之间的潜在关联，包括年龄、性别、体重指数、诊断和住院时间。
病例交叉研究显示，与 COVID-19 前 12 周相比，COVID-19 后 8 周时腹股沟疼痛加重的风险增加（相对风险 [RR]，9.5；95%置信区间 [CI]，2.259-39.954）。对于 COVID-19 阳性患者，多变量分析显示，住院时间是与腹股沟疼痛加重风险增加显著相关的独立因素（优势比 [OR]，1.26；95%CI，1.03-1.55，p=0.027）。
本研究证实了 COVID-19 与 THA 患者腹股沟区域疼痛加剧之间的关联，并延长了住院时间是一个可能的促成因素。本研究通过调查 COVID-19 后 THA 患者腹股沟疼痛加重的风险，扩展了当前文献，为这一特定人群的术后结果提供了有价值的见解。
本回顾性研究得到上海总医院机构审查委员会的批准（编号 2023-264）。
