Laboratory for Advanced Nanomaterials and Sustainable Energy Technologies, Institute for Computational Science and Artificial Intelligence, Van Lang University, Ho Chi Minh City, 70000, Vietnam.
Faculty of Applied Technology, School of Technology, Van Lang University, Ho Chi Minh City, 70000, Vietnam.
Phys Chem Chem Phys. 2024 Jul 3;26(26):18449-18458. doi: 10.1039/d3cp04340a.
In this study, we developed a high-performance non-enzymatic electrochemical sensor based on urchin-like CoP/CuP heterostructured nanorods supported on a three-dimensional porous copper foam, namely, CoP/CuP NRs/CF, for the detection of dopamine. Benefiting from the promising intrinsic catalytic activities of CoP and CuP, urchin-like microsphere structures, and a large electrochemically active surface area for exposing numerous accessible catalytic active sites, the proposed CoP/CuP NRs/CF shows extraordinary electrochemical response towards the electrocatalytic oxidation of dopamine. As a result, the CoP/CuP NRs/CF sensing electrode has a broad detection window (from 0.2 to 2000 μM), low detection limit (0.51 μM), high electrochemical sensitivity (0.0105 mA μM cm), excellent selectivity towards dopamine in the coexistence of some interfering species, and good stability for dopamine determination. More importantly, the CoP/CuP NRs/CF catalyst also exhibits excellent catalytic activity, sensitivity, and selectivity for dopamine detection under simulated human body conditions at a physiological pH of 7.25 (0.1 M PBS) at 36.6 °C.
在这项研究中，我们开发了一种基于三维多孔铜泡沫负载的具有海胆状 CoP/CuP 异质结构纳米棒的高性能非酶电化学传感器，即 CoP/CuP NRs/CF，用于检测多巴胺。得益于 CoP 和 CuP 的内在催化活性、海胆状微球结构以及暴露大量可及的催化活性位点的大电化学活性表面积，所提出的 CoP/CuP NRs/CF 对多巴胺的电化学催化氧化表现出非凡的电化学响应。结果，CoP/CuP NRs/CF 传感电极具有宽的检测窗口（从 0.2 到 2000 μM）、低检测限（0.51 μM）、高电化学灵敏度（0.0105 mA μM cm）、对共存的一些干扰物质的多巴胺具有出色的选择性，以及用于多巴胺测定的良好稳定性。更重要的是，在 36.6°C 生理 pH 值为 7.25（0.1 M PBS）的模拟人体条件下，CoP/CuP NRs/CF 催化剂对多巴胺检测也表现出优异的催化活性、灵敏度和选择性。
