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乌干达严重传染病队列中东方体属地方性流行的证据。

Evidence of Orientia spp. Endemicity among Severe Infectious Disease Cohorts, Uganda.

出版信息

Emerg Infect Dis. 2024 Jul;30(7):1442-1446. doi: 10.3201/eid3007.231040.

DOI:10.3201/eid3007.231040
PMID:38916638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11210639/
Abstract

At 3 severe infection cohort sites in Uganda, Orientia seropositivity was common. We identified 4 seroconversion cases and 1 PCR-positive case. These results provide serologic and molecular support for Orientia spp. circulating in sub-Saharan Africa, possibly expanding its endemic range. Orientia infections could cause severe illness and hospitalizations in this region.

摘要

在乌干达的 3 个严重感染队列地点，东方体血清阳性很常见。我们发现了 4 例血清转换病例和 1 例 PCR 阳性病例。这些结果为奥氏立克次体在撒哈拉以南非洲的传播提供了血清学和分子支持，可能扩大了其地方性范围。奥氏立克次体感染可能导致该地区发生严重疾病和住院治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9699/11210639/4d383cf24d21/23-1040-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9699/11210639/cfe570aeee87/23-1040-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9699/11210639/4d383cf24d21/23-1040-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9699/11210639/cfe570aeee87/23-1040-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9699/11210639/4d383cf24d21/23-1040-F2.jpg

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Development of a New Genus-Specific Quantitative Real-Time PCR Assay for the Diagnosis of Scrub Typhus in South America.开发一种用于南美洲恙虫病诊断的新型属特异性定量实时聚合酶链反应检测方法。
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