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大肠杆菌与脆弱拟杆菌之间的致病协同作用:在实验小鼠模型中的研究

Pathogenic synergy between Escherichia coli and Bacteroides fragilis: studies in an experimental mouse model.

作者信息

Verweij-van Vught A M, Namavar F, Sparrius M, Vel W A, MacLaren D M

出版信息

J Med Microbiol. 1985 Jun;19(3):325-31. doi: 10.1099/00222615-19-3-325.

Abstract

An animal model is described for quantitative evaluation of pathogenic synergy between Escherichia coli and Bacteroides fragilis in which adjuvants were not required for abscess formation. Two sets of strains of E. coli and B. fragilis isolated from human wound infections were tested. Pathogenic synergy was observed in only one of the two combinations and was dependent on properties of E. coli.

摘要

描述了一种用于定量评估大肠杆菌和脆弱拟杆菌之间致病协同作用的动物模型,其中脓肿形成不需要佐剂。测试了从人类伤口感染中分离出的两组大肠杆菌和脆弱拟杆菌菌株。在两种组合中仅在其中一组中观察到致病协同作用,并且其取决于大肠杆菌的特性。

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