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评估韩国人饮食中的双酚 A 暴露情况:使用韩国国家健康和营养检查调查进行全面数据库构建和分析。

Assessing dietary bisphenol A exposure among Koreans: comprehensive database construction and analysis using the Korea National Health and Nutrition Examination Survey.

机构信息

Department of Food Science and Biotechnology, Ewha Womans University, Seoul, Korea.

出版信息

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2024 Aug;41(8):1018-1055. doi: 10.1080/19440049.2024.2362252. Epub 2024 Jun 26.

Abstract

Bisphenol A (BPA) exposure primarily occurs through dietary intake. This study aimed to estimate the extent of dietary BPA exposure among Koreans. A thorough literature search was conducted to establish a BPA content database encompassing common foods consumed in Korea, including various food raw materials and processed food products. Dietary exposure levels were estimated by integrating the constructed BPA database with comprehensive nationwide 24 h-dietary recall datasets. The finding revealed that dietary BPA exposure was low for most Koreans, with a mean of 14.5 ng/kg bw/day, but was higher for preschool-age children (over 23 ng). Canned foods accounted for 9-36% of the total dietary exposure of the highest dietary exposure groups; while across all age groups, a considerable amount was derived from canned tuna, contribution of canned fruits and canned coffee (milk-containing) was high for preschool-age children and adults, respectively. Notably, for adults, a substantial proportion also stemmed from beer packaged in cans. While diet contributed over 80% of aggregate exposure for most age groups, preschool-age children experienced 60% exposure through diet due to additional exposure from indoor dust. Even at the high exposure scenario, aggregate BPA exposure levels remained lower than the current tolerable daily intake (TDI) set by the Korean agency (20 μg/kg bw/day). Nevertheless, most Koreans were exposed to BPA levels surpassing the strictest TDI (0.2 ng/kg bw/day) set by the European Food Safety Authority.

摘要

双酚 A(BPA)暴露主要通过饮食摄入。本研究旨在评估韩国人饮食中 BPA 暴露的程度。通过对韩国常见食品的 BPA 含量进行全面的文献检索,建立了一个 BPA 含量数据库,包括各种食品原料和加工食品。通过将构建的 BPA 数据库与全国范围的 24 小时饮食回忆数据集相结合,估算了饮食中 BPA 的暴露水平。研究结果表明,大多数韩国人的饮食 BPA 暴露水平较低,平均为 14.5ng/kg bw/day,但学龄前儿童的暴露水平较高(超过 23ng)。罐装食品占最高饮食暴露组总饮食暴露的 9-36%;在所有年龄组中,大量的 BPA 来源于罐装金枪鱼,而罐装水果和含牛奶的罐装咖啡对学龄前儿童和成年人的贡献较大。值得注意的是,对于成年人来说,大量的 BPA 也来自罐装啤酒。虽然饮食对大多数年龄组的总暴露量贡献超过 80%,但由于室内灰尘的额外暴露,学龄前儿童的饮食暴露量达到了 60%。即使在高暴露情况下,总 BPA 暴露水平仍低于韩国机构设定的可耐受日摄入量(TDI)(20μg/kg bw/day)。然而,大多数韩国人暴露于 BPA 水平超过了欧洲食品安全局设定的最严格的 TDI(0.2ng/kg bw/day)。

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