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预防老年人慢性肾脏病及其并发症。

Prevention of Chronic Kidney Disease and Its Complications in Older Adults.

机构信息

Division of Nephrology and Immunology, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

Division of General Internal Medicine-Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

Drugs Aging. 2024 Jul;41(7):565-576. doi: 10.1007/s40266-024-01128-7. Epub 2024 Jun 26.

DOI:10.1007/s40266-024-01128-7
PMID:38926293
Abstract

In an era marked by a global demographic shift towards an aging society, there is a heightened prevalence of chronic kidney disease (CKD) among older adults. The burden of CKD spans from kidney-related complications to impacting psychological well-being, giving rise to depressive symptoms and caregiver burnout. This article delves into CKD prevention strategies within the context of aging, contributing to the discourse by exploring its multifaceted aspects. The prevention of CKD in the older adults necessitates a comprehensive approach. Primary prevention is centered on the modification of risk factors, acknowledging the intricate interplay of various comorbidities. Secondary prevention focuses on early CKD identification. Tertiary prevention aims to address factors contributing to CKD progression and complications, emphasizing the importance of timely interventions. This comprehensive strategy aims to enhance the quality of life for individuals affected by CKD, decelerating the deterioration of functional status. By addressing CKD at multiple levels, this approach seeks to effectively and compassionately care for the aging population.

摘要

在一个老龄化社会的全球人口结构转变的时代,老年人中慢性肾脏病(CKD)的发病率显著升高。CKD 的负担不仅涉及肾脏相关并发症,还会影响心理健康,导致抑郁症状和照顾者倦怠。本文探讨了老龄化背景下的 CKD 预防策略,通过探索其多方面的角度为相关讨论做出贡献。预防老年人 CKD 需要采取综合方法。一级预防以改变风险因素为中心,认识到各种合并症的复杂相互作用。二级预防侧重于早期 CKD 的识别。三级预防旨在解决导致 CKD 进展和并发症的因素,强调及时干预的重要性。这种综合策略旨在提高受 CKD 影响的个体的生活质量,减缓功能状态的恶化。通过在多个层面上解决 CKD 问题,这种方法旨在为老龄化人口提供有效和富有同情心的护理。

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本文引用的文献

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Nephrol Dial Transplant. 2024 Oct 30;39(11):1867-1875. doi: 10.1093/ndt/gfae077.
2
Association between the composite dietary antioxidant index and chronic kidney disease: evidence from NHANES 2011-2018.复合膳食抗氧化指数与慢性肾脏病之间的关联:来自2011 - 2018年美国国家健康与营养检查调查(NHANES)的证据
Food Funct. 2023 Oct 16;14(20):9279-9286. doi: 10.1039/d3fo01157g.
3
Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
慢性肾脏病新型贫血治疗方法:改善全球肾脏病预后组织(KDIGO)争议会议的结论。
Kidney Int. 2023 Oct;104(4):655-680. doi: 10.1016/j.kint.2023.05.009. Epub 2023 May 24.
4
Association between CKD-MBD and mortality in older patients with advanced CKD-results from the EQUAL study.慢性肾脏病-矿物质和骨异常与晚期慢性肾脏病老年患者死亡的相关性:EQUAL 研究结果。
Nephrol Dial Transplant. 2023 Oct 31;38(11):2562-2575. doi: 10.1093/ndt/gfad100.
5
Exploring Patients' Perceptions About Chronic Kidney Disease and Their Treatment: A Qualitative Study.探索患者对慢性肾脏病及其治疗的认知:一项定性研究。
Int J Behav Med. 2024 Apr;31(2):263-275. doi: 10.1007/s12529-023-10178-x. Epub 2023 May 24.
6
Nutritional status and the risk of malnutrition in older adults with chronic kidney disease - implications for low protein intake and nutritional care: A critical review endorsed by ERN-ERA and ESPEN.慢性肾脏病老年患者的营养状况与营养不良风险——低蛋白摄入及营养护理的意义:欧洲肾脏营养网络(ERN-ERA)和欧洲临床营养与代谢学会(ESPEN)认可的批判性综述
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