Dahl M G, Cook L J
Br J Dermatol. 1979 Oct;101(4):469-73. doi: 10.1111/j.1365-2133.1979.tb00029.x.
Three patients are described with pemphigoid (two with typical adult type and one with juvenile pemphigoid) in whom bullous lesions had clearly been induced by the trauma of scratching. In two patients this phenomenon occurred during the first few weeks of systemic corticosteroid treatment at a time when other lesions were resolving or had completely healed. Although lesions induced by trauma are not usually of great clinical importance, epidermolysis bullosa acquisita may represent a variant of pemphigoid in which trauma-induced lesions predominate. Induction of pemphigoid lesions by trauma may prove a useful method of studying early immunopathological events.
本文描述了3例类天疱疮患者（2例为典型成人型，1例为青少年型），其水疱性损害显然是由搔抓创伤所致。在2例患者中，这种现象发生在全身使用皮质类固醇治疗的最初几周，此时其他损害正在消退或已完全愈合。虽然创伤诱发的损害通常在临床上并不十分重要，但获得性大疱性表皮松解症可能是类天疱疮的一种变异型，其中创伤诱发的损害占主导。创伤诱发类天疱疮损害可能是研究早期免疫病理事件的一种有用方法。
