Barth J H, Kelly S E, Wojnarowska F, Savin J A, Whittaker S, Cream J J, White J E
Department of Dermatology, Slade Hospital, Oxford, Headington, United Kingdom.
J Am Acad Dermatol. 1988 Aug;19(2 Pt 1):303-8. doi: 10.1016/s0190-9622(88)70176-0.
We report eight patients with ulcerative colitis who have subsequently developed pemphigoid. Four patients were investigated to determine the pattern of pemphigoid antibody staining on whole and chemically split skin and oral mucosa to distinguish between pemphigoid and epidermolysis bullosa acquisita. The findings were suggestive of pemphigoid with a predominantly epidermal pattern. Three patients were studied for the presence of antibodies against the colon (which were absent). The relationship between pemphigoid and ulcerative colitis is discussed in relation to a case-control study.
我们报告了8例溃疡性结肠炎患者，这些患者随后发生了类天疱疮。对4例患者进行了研究，以确定类天疱疮抗体在完整皮肤、化学分离皮肤及口腔黏膜上的染色模式，以区分类天疱疮和获得性大疱性表皮松解症。研究结果提示为主要表现为表皮型的类天疱疮。对3例患者检测了抗结肠抗体（结果均为阴性）。结合一项病例对照研究讨论了类天疱疮与溃疡性结肠炎之间的关系。
