Tathong Tanom, Khamhan Supawut, Soisungwan Salinee, Phoemchalard Chirasak
Department of Food Technology, Faculty of Agriculture and Technology, Nakhon Phanom University, Nakhon Phanom 48000, Thailand.
That Phanom College, Nakhon Phanom University, Nakhon Phanom 48110, Thailand.
Animals (Basel). 2024 Jun 7;14(12):1718. doi: 10.3390/ani14121718.
Stress experienced by animals during pre-mortem management handling significantly affects both their welfare and the quality of the meat produced. Using hemp-derived CBD may offer several benefits in alleviating this issue. In this study, we investigated the effects of hemp-derived CBD supplementation on blood variables, growth performance, carcass characteristics, and meat quality in goats. Sixteen crossbred Boer goats were divided into four groups receiving a basal diet supplemented with 0 (control), 0.1, 0.2, or 0.3 mL CBD/30 kg body weight over 90 days. Although growth, carcass characteristics, and pH remained unaffected, CBD supplementation influenced several blood variables. Specifically, dietary CBD at 0.1-0.3 mL increased white blood cell (WBC) counts, while 0.3 mL CBD increased serum total protein, globulin, sodium, and carbon dioxide levels, potentially affecting protein metabolism and electrolyte balance. Over time, significant changes were noted in hematological profiles, kidney markers, protein profiles, and some electrolytes, indicating physiological adaptations. Regarding meat quality, supplementation with 0.2-0.3 mL of CBD linearly improved color redness and stability; moreover, CBD supplementation improved tenderness and textural properties, resulting in a softer meat texture. However, analysis using an E-nose indicated increased ammonia and organic solvent vapors in meat from the higher CBD groups. This study concluded that CBD supplementation up to 0.3 mL of CBD/30 kg body weight beneficially modulated blood biomarkers, meat color, and tenderness without adverse impacts on growth or carcass characteristics in goats.
动物在宰前管理处理过程中所经历的应激会显著影响其福利以及所产肉类的质量。使用源自大麻的大麻二酚（CBD）可能在缓解这一问题方面具有多种益处。在本研究中，我们调查了源自大麻的CBD补充剂对山羊血液变量、生长性能、胴体特征和肉质的影响。16只杂交波尔山羊被分为四组，在90天内接受补充了0（对照组）、0.1、0.2或0.3 mL CBD/30千克体重的基础日粮。尽管生长、胴体特征和pH值未受影响，但CBD补充剂影响了多个血液变量。具体而言，日粮中添加0.1 - 0.3 mL CBD可增加白细胞（WBC）计数，而0.3 mL CBD可提高血清总蛋白、球蛋白、钠和二氧化碳水平，这可能会影响蛋白质代谢和电解质平衡。随着时间的推移，血液学指标、肾脏标志物、蛋白质谱和一些电解质出现了显著变化，表明存在生理适应性。关于肉质，补充0.2 - 0.3 mL CBD可线性改善肉的红色度和稳定性；此外，CBD补充剂还改善了嫩度和质地特性，使肉质更软。然而，使用电子鼻分析表明，较高CBD组的肉中氨和有机溶剂蒸汽增加。本研究得出结论，补充高达0.3 mL CBD/30千克体重的CBD可有益地调节血液生物标志物、肉色和嫩度，而对山羊的生长或胴体特征没有不利影响。
