Hsu Jui-Chi, Chang Po-Hsun, Tai Chien-Hsiang, Chen Yi-Chun
Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Life (Basel). 2024 Jun 7;14(6):738. doi: 10.3390/life14060738.
Histoplasmosis is a global infection caused by the thermally dimorphic fungus, complex. It is endemic in the United States, as well as in Central and South America. In Taiwan, histoplasmosis is rare, with the first reported case not occurring until 1977. We summarized a total of 17 cases reported in Taiwan over the past 40 years and provided detailed descriptions for four probable indigenous cases. Due to the lack of rapid diagnostic tools and clinical suspicion, histoplasmosis may be underdiagnosed in Taiwan. We recognize that a limitation of our review is the lack of data on the environmental surveillance for complex in Taiwan. Conducting a further phylogenetic analysis on both environmental and clinical isolates would provide valuable evidence for the region.
组织胞浆菌病是一种由双态真菌荚膜组织胞浆菌复合体引起的全球性感染。它在美国以及中美洲和南美洲呈地方性流行。在台湾，组织胞浆菌病很罕见，首例报告病例直到1977年才出现。我们总结了台湾过去40年报告的总共17例病例，并对4例可能的本土病例进行了详细描述。由于缺乏快速诊断工具且临床怀疑不足，组织胞浆菌病在台湾可能未得到充分诊断。我们认识到我们综述的一个局限性是缺乏台湾荚膜组织胞浆菌复合体的环境监测数据。对环境和临床分离株进行进一步的系统发育分析将为该地区提供有价值的证据。
