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[同种异体移植肾的病理组织学。来自古巴圣地亚哥的10年报告]

[Pathohistology of allotransplanted kidneys. A 10-year report from Santiago, Cuba].

作者信息

Nizze H, Vigier Perez E M

出版信息

Z Urol Nephrol. 1985 Apr;78(4):205-13.

PMID:3892973
Abstract

Of altogether 201 allotransplantations in Santiago de Cuba the material was histologically examined 328 times. Transplant biopsies and explants most frequently revealed a rejection nephropathy, in which case the forms of the prognostically unfavourable rejection vasculopapty were more frequent than the types of the tubulointerstitial rejection nephropath which are better to be influenced therapeutically. A histologically diagnosed acute failure of the kidney was casually based on (reversible) lesions of the donor kidney, infections and haemorrhages after the transplantation as well as on the combination with a rejection. A transplant pyelonephritis and transplant glomerulonephritis were rarely observed. Complete necroses of a transplant biopsy cylinder allow the urgent suspicion of an obliterating rejection vasculopathy with secondary transplant necroses.

摘要

在古巴圣地亚哥的201例同种异体移植中,对材料进行了328次组织学检查。移植活检和切除标本最常显示排斥性肾病,在这种情况下,预后不良的血管乳头型排斥比肾小管间质性排斥性肾病的类型更常见,而后者在治疗上更容易受到影响。组织学诊断的急性肾衰竭偶然是基于供体肾的(可逆性)病变、移植后的感染和出血以及与排斥反应的合并情况。移植肾盂肾炎和移植肾小球肾炎很少见。移植活检圆柱体的完全坏死应引起对闭塞性排斥性血管病伴继发性移植坏死的紧急怀疑。

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