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腹腔镜袖状胃切除术治疗青少年和年轻成年人的体重最低点和长期体重结局。

Weight Nadir and Long-Term Weight Outcomes After Laparoscopic Sleeve Gastrectomy in a Diverse Cohort of Adolescents and Young Adults.

机构信息

Division of Pediatric Surgery, Yale School of Medicine, 330 Cedar St, FMB 131, New Haven, CT, 06510, USA.

Department of Surgery, Yale School of Medicine, 330 Cedar St, New Haven, CT, 06510, USA.

出版信息

Obes Surg. 2024 Aug;34(8):2965-2973. doi: 10.1007/s11695-024-07374-3. Epub 2024 Jun 27.

DOI:10.1007/s11695-024-07374-3
PMID:38935262
Abstract

INTRODUCTION

Laparoscopic sleeve gastrectomy (LSG) is currently the most common bariatric procedure performed in adolescents and young adults in the United States (USA), but there are limited data available on long-term postoperative weight outcomes in these patients. This single-institution US study follows longitudinal weight data in a diverse group of patients undergoing LSG at age 25 years or younger.

METHODS

We retrospectively reviewed records of all patients 25 years or younger who underwent LSG at our institution between 2013 and 2020. All weight data documented in the medical record through January 2023 was included. We calculated weight change postoperatively as percent total weight loss (%TWL) relative to preoperative weight.

RESULTS

One hundred forty-one patients underwent LSG, at a mean age of 23.1 years. Within this cohort, 56.1% identified as non-Hispanic Black or Hispanic, and 39.7% had private health insurance. The mean %TWL at weight nadir was 28.5% at a mean of 1.35 years postoperatively. The mean long-term %TWL (in patients with ≥ 4 years of follow-up) was 11.8% at a mean of 5.6 years postoperatively, with 43 of the 84 patients with long-term weight data (51%) within 10% of their preoperative weight at most recent follow-up.

CONCLUSION

Adolescents and young adults undergoing LSG at our institution had weight nadir comparable to published results during the first 1 to 2 years postoperatively, but the majority developed significant weight recurrence over the ensuing years. Our findings highlight the need for adjuvant weight loss strategies to improve the durability of weight outcomes after LSG in this population.

摘要

简介

腹腔镜袖状胃切除术(LSG)目前是美国青少年和年轻成年人最常见的减肥手术,但关于这些患者术后长期体重结果的数据有限。这项美国单机构研究对在 25 岁或以下年龄在我们机构接受 LSG 的患者进行了长期体重数据随访。

方法

我们回顾性地审查了我们机构在 2013 年至 2020 年间接受 LSG 的所有 25 岁或以下患者的记录。所有病历中记录的体重数据均包括在内。我们通过将术后体重变化计算为相对于术前体重的百分比总减重(%TWL)。

结果

141 名患者接受了 LSG,平均年龄为 23.1 岁。在这一组中,56.1%为非西班牙裔黑人和西班牙裔,39.7%有私人医疗保险。体重最低点的平均%TWL 为 28.5%,术后平均 1.35 年。平均长期%TWL(在有≥4 年随访的患者中)为术后 5.6 年时的 11.8%,84 名长期体重数据患者中有 43 名(51%)在最近一次随访时体重与术前相差 10%以内。

结论

我们机构接受 LSG 的青少年和年轻成年人在术后 1 至 2 年内体重最低点与已发表的结果相当,但在随后的几年中,大多数患者体重出现明显反弹。我们的发现强调需要辅助减肥策略,以提高该人群 LSG 后体重结果的耐久性。

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本文引用的文献

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Semaglutide and Tirzepatide for the Management of Weight Recurrence After Sleeve Gastrectomy: A Retrospective Cohort Study.司美格鲁肽和替尔泊肽治疗胃旁路术后体重复发:一项回顾性队列研究。
Obes Surg. 2024 Apr;34(4):1324-1332. doi: 10.1007/s11695-024-07137-0. Epub 2024 Mar 2.
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Long-Term Outcomes of Sleeve Gastrectomy: Weight Recurrence and Surgical Non-responders.袖状胃切除术的长期结果:体重复发与手术无反应者。
Obes Surg. 2023 Oct;33(10):3028-3034. doi: 10.1007/s11695-023-06730-z. Epub 2023 Jul 18.
3
Long-term Outcomes of Sleeve Gastrectomy in Adolescent Patients: The Effect of Weight Loss in Younger Years to Outcomes in Adulthood.
青少年患者胃袖状切除术的长期疗效:减肥对年轻患者成年后结局的影响。
BMC Surg. 2023 Apr 28;23(1):103. doi: 10.1186/s12893-023-02006-6.
4
Effectiveness of semaglutide versus liraglutide for treating post-metabolic and bariatric surgery weight recurrence.司美格鲁肽对比利拉鲁肽治疗代谢后和减重手术后体重复发的疗效。
Obesity (Silver Spring). 2023 May;31(5):1280-1289. doi: 10.1002/oby.23736. Epub 2023 Mar 30.
5
Long-term Outcomes Following Adolescent Metabolic and Bariatric Surgery.青少年代谢和减重手术后的长期结果。
J Clin Endocrinol Metab. 2023 Aug 18;108(9):2184-2192. doi: 10.1210/clinem/dgad155.
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The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program Bariatric Surgical Risk/Benefit Calculator: 1-year weight.代谢与减重外科认证和质量改进计划减重手术风险/获益计算器:1 年体重。
Surg Obes Relat Dis. 2023 Jul;19(7):690-696. doi: 10.1016/j.soard.2022.12.028. Epub 2022 Dec 17.
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Once-Weekly Semaglutide in Adolescents with Obesity.每周一次司美格鲁肽治疗肥胖青少年。
N Engl J Med. 2022 Dec 15;387(24):2245-2257. doi: 10.1056/NEJMoa2208601. Epub 2022 Nov 2.
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Long-Term Outcomes after Adolescent Bariatric Surgery.青少年减重手术后的长期结果。
J Am Coll Surg. 2022 Oct 1;235(4):592-602. doi: 10.1097/XCS.0000000000000325. Epub 2022 Sep 15.
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American Society for Metabolic and Bariatric Surgery 2020 estimate of metabolic and bariatric procedures performed in the United States.美国代谢与减重外科学会 2020 年美国代谢与减重手术量预估。
Surg Obes Relat Dis. 2022 Sep;18(9):1134-1140. doi: 10.1016/j.soard.2022.06.284. Epub 2022 Jun 26.
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