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腹腔镜袖状胃切除术 5 年的结果:成人与青少年的比较。

Five-year Outcomes of Laparoscopic Sleeve Gastrectomy: a Comparison Between Adults and Adolescents.

机构信息

Department of Bariatric and Metabolic Surgery, Hamad Medical Corporation, Doha, Qatar.

Department of General Surgery, Hamad Medical Corporation, Doha, Qatar.

出版信息

Obes Surg. 2018 Jul;28(7):2040-2045. doi: 10.1007/s11695-018-3139-6.

DOI:10.1007/s11695-018-3139-6
PMID:29430596
Abstract

BACKGROUND

Bariatric surgery in adolescents is still under debate. Literature about the long-term impact of laparoscopic sleeve gastrectomy (LSG) on adolescents' obesity and associated morbidities is scarce. It is unknown if LSG shows better long-term results in the adolescent or adult group.

AIM

To compare the long-term effectiveness of LSG on obesity and associated comorbidities between adolescents and adults.

METHODS

This retrospective study analyzed all patients with morbid obesity who underwent LSG in (2011-2012) and were followed for up to 5 years. Patients were divided into two groups: adolescents and adults. Data were compared between the two groups.

RESULTS

LSG was performed in 139 adults and 91 adolescents. The mean ages of the adults and adolescents were 37.4 ± 11.4 and 17 ± 1.5 years, respectively. The preoperative body mass index values of the adults and adolescents were 48.4 ± 8.7 and 47.6 ± 7.5 kg/m2, respectively (P = 0.95). At 5 years, percentage of total weight loss increased in adolescents (to 35.8 ± 11.5%), while it remained almost the same in adults (26.3 ± 10%). At 1 year, about 68.2% of adults and 62.5% of adolescents were cured from diabetes though, 13% of diabetic adults had relapse at 5 years and none of the adolescents relapsed. Postoperative complications occurred in both groups.

CONCLUSION

LSG showed comparable weight loss results in adults and adolescents, with better results in adolescents. LSG is more effective in preventing and treating diabetes/prediabetes in the adolescent group.

摘要

背景

青少年的减重手术仍存在争议。关于腹腔镜袖状胃切除术(LSG)对青少年肥胖及其相关合并症的长期影响的文献很少。目前尚不清楚 LSG 在青少年或成年组是否具有更好的长期效果。

目的

比较 LSG 在青少年和成年人中治疗肥胖及其相关合并症的长期效果。

方法

这项回顾性研究分析了所有于(2011-2012 年)接受 LSG 治疗且随访时间长达 5 年的病态肥胖患者。患者被分为两组:青少年组和成年组。对两组数据进行比较。

结果

共对 139 名成年患者和 91 名青少年患者进行了 LSG。成年患者和青少年患者的平均年龄分别为 37.4±11.4 岁和 17±1.5 岁。成年患者和青少年患者术前的体重指数值分别为 48.4±8.7kg/m2和 47.6±7.5kg/m2(P=0.95)。5 年后,青少年的体重总减轻率增加(达到 35.8±11.5%),而成人组的体重减轻率基本保持不变(26.3±10%)。术后 1 年,约 68.2%的成年患者和 62.5%的青少年患者的糖尿病得到治愈,然而,13%的成年糖尿病患者在 5 年后出现复发,而青少年患者中无一例复发。两组患者均发生术后并发症。

结论

LSG 在成年患者和青少年患者中均显示出相当的减重效果,且青少年组的效果更好。LSG 在预防和治疗青少年组的糖尿病/糖尿病前期方面更有效。

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本文引用的文献

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Adolescent bariatric surgery: a systematic review of recommendation documents.青少年减重手术:推荐文件的系统评价。
Surg Obes Relat Dis. 2017 Oct;13(10):1768-1779. doi: 10.1016/j.soard.2017.08.008. Epub 2017 Aug 12.
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Obes Surg. 2018 Feb;28(2):474-482. doi: 10.1007/s11695-017-2868-2.
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A 5-Year Follow-Up Study of Laparoscopic Sleeve Gastrectomy Among Morbidly Obese Adolescents: Does It Improve Body Image and Prevent and Treat Diabetes?
2型糖尿病青年患者行袖状胃切除术后3个月,血糖、胰岛素敏感性及分泌功能得到改善。
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