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The limitations of evidence-based medicine compel the practice of personalized medicine.

作者信息

Einav Sharon, O'Connor Michael

机构信息

Maccabi Healthcare Services Sharon Region, Hebrew University Faculty of Medicine and Medint Medical Intelligence, Jerusalem, Israel.

Department of Anesthesia and Critical Care, University of Chicago, Chicago, USA.

出版信息

Intensive Care Med. 2024 Aug;50(8):1323-1326. doi: 10.1007/s00134-024-07528-y. Epub 2024 Jun 27.

DOI:10.1007/s00134-024-07528-y
PMID:38935271
Abstract
摘要

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JAMA. 2024 Jun 4;331(21):1845-1853. doi: 10.1001/jama.2024.7741.
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Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.揭示脓毒症的异质性：亚表型的比较分析。
Intensive Care Med. 2023 Nov;49(11):1360-1369. doi: 10.1007/s00134-023-07239-w. Epub 2023 Oct 18.
3
Target Trial Emulation: A Framework for Causal Inference From Observational Data.目标试验模拟：一种从观察性数据进行因果推断的框架。
JAMA. 2022 Dec 27;328(24):2446-2447. doi: 10.1001/jama.2022.21383.
4
Randomised clinical trials in critical care: past, present and future.危重病随机临床试验：过去、现在和未来。
Intensive Care Med. 2022 Feb;48(2):164-178. doi: 10.1007/s00134-021-06587-9. Epub 2021 Dec 2.
5
Which Multicenter Randomized Controlled Trials in Critical Care Medicine Have Shown Reduced Mortality? A Systematic Review.哪些重症监护医学多中心随机对照试验显示降低了死亡率？系统评价。
Crit Care Med. 2019 Dec;47(12):1680-1691. doi: 10.1097/CCM.0000000000004000.
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UpToDate adherence to GRADE criteria for strong recommendations: an analytical survey.《UpToDate》对强烈推荐的GRADE标准的遵循情况：一项分析性调查。
BMJ Open. 2017 Nov 16;7(11):e018593. doi: 10.1136/bmjopen-2017-018593.
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Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care.治疗效果异质性对重症监护随机试验报告与分析的影响
Am J Respir Crit Care Med. 2015 Nov 1;192(9):1045-51. doi: 10.1164/rccm.201411-2125CP.
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An Observational Study of Decision Making by Medical Intensivists.医学重症监护医师决策的观察性研究
Crit Care Med. 2015 Aug;43(8):1660-8. doi: 10.1097/CCM.0000000000001084.
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Can anesthesiologists help? Analysis of the american heart association-emergency cardiac care recommendations for cardiopulmonary resuscitation, with a focus on management of airway and breathing.麻醉医生能提供帮助吗？对美国心脏协会心肺复苏紧急心脏护理建议的分析，重点关注气道和呼吸管理。
Anesth Analg. 2015 Feb;120(2):484-90. doi: 10.1213/ANE.0000000000000560.
10
The good, the bad and the ugly: meta-analyses.元分析的优劣与不足
Hum Reprod. 2014 Aug;29(8):1622-6. doi: 10.1093/humrep/deu127. Epub 2014 Jun 4.