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诺丁汉电休克治疗研究。抑郁症中双侧、单侧和模拟电休克治疗的双盲比较。

The Nottingham ECT Study. A double-blind comparison of bilateral, unilateral and simulated ECT in depressive illness.

作者信息

Gregory S, Shawcross C R, Gill D

出版信息

Br J Psychiatry. 1985 May;146:520-4. doi: 10.1192/bjp.146.5.520.

DOI:10.1192/bjp.146.5.520
PMID:3893601
Abstract

Sixty nine patients took part in a double-blind study to investigate the efficacy of bilateral, unilateral, and simulated ECT in the treatment of depressive illness. The findings suggest that both bilateral and unilateral ECT are highly effective treatments for depression and are significantly superior to simulated ECT. There was also evidence that patients receiving bilateral ECT recovered more rapidly than those receiving unilateral ECT and required significantly fewer treatments. The relevance of these findings to clinical practice is discussed.

摘要

69名患者参与了一项双盲研究,以调查双侧、单侧及模拟电休克疗法(ECT)治疗抑郁症的疗效。研究结果表明,双侧和单侧ECT都是治疗抑郁症的高效疗法,且显著优于模拟ECT。也有证据显示,接受双侧ECT治疗的患者比接受单侧ECT治疗的患者康复得更快,且所需治疗次数明显更少。文中讨论了这些研究结果与临床实践的相关性。

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Br J Psychiatry. 1985 May;146:520-4. doi: 10.1192/bjp.146.5.520.
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